There is a vast literature on the pharmacology of
silver reviewed in Hill and Pillsbury' Argyria & The
Pharmacology Of Silver, Williams and Wilkins,
Baltimore, 1939. Both colloidal and non-colloidal
silver pharmacological effects are reviewed.

A typical investigation was that of Archard and Wail,
Arch. de Med. Exper. & d'Anat. Path., 12, 319, 1907.
mentioned in the fourth chapter of Hill & Pillsbury,
The Pharmaco-Physiologic Effects Of Silver
Administration. Archard and Wail did early work on
colloidal silver, years before Searle's acclaimed
clinical treatise of 1919.
Archard and Wail investigated the effect of colloidal
silver on white blood cell counts, red blood cell counts,
bone marrow, Malpighian corpuscles, splenic pulp
and the thymus gland and other effects.

Best regards,

Matthew