Re: CS>iontophoresis
From: Jason
Date: Thu, 20 Jan 2005 22:56:37

  [...]

  > All of  the  devices I currently have still can  produce  too much
  > current; the  current  is fine for tissues that  are  healthy, but
  > with damaged tissue, the conductivity increases, and dramatically.

  > The ideal  device would allow absolute current  control, according
  > to the specs laid out by Dr. Robert O. Becker, and be used  with a
  > conductive gel  and two silver electrodes.  The  electrode spacing
  > should be  adjusted  to the edges of the  area  being  treated. DC
  > current should  be used, with a pulsing mechanism to  help control
  > the current  travel (paths of current flow) in the  body  (we only
  > want to  deliver a small amount of silver ions into the  body, not
  > utilize the  current  and electricity  for  therapuetic purposes).
  > Based only  upon my rough estimates from  personal  experience, it
  > takes between  2-5 seconds for paths of current to  be established
  > in the  body's  tissues. 10 second pulses,  I  estimate,  would be
  > about right if one is using the "proper" amount of  current, with,
  > perhaps, two second pauses... HOWEVER, this is based only  upon my
  > subjective and  limited experimentation, and much more  work needs
  > to be done.

  > All of that said, my experimentations to date HAVE  been amazingly
  > effective. Bacteria  and  virii can  be  effectively  killed using
  > "silver iontophoresis", where silver applied topically fails.

  > However, I  still do not have a device that performs  the  way I'd
  > like it  to;  potentiometers  can   be  used  to  allow "scalable"
  > adjustments to  the amount of current being  delivered,  and there
  > should be  an  "indicator"  that   indicates  when  a  circuit has
  > actually been  established.  We  then need  to  study  the miminal
  > amount of current flow required to effectively deliver silver ions
  > to the "treatment area". This will, likely, vary from situation to
  > situation.

  > I like to leave the "engineering" of such things to those  who are
  > proficient in engineering. Such devices exist, but they are wildly
  > over-priced, at least for "my" purposes!

  [...]

  > Best Regards,

  > Jason

  Jason,

  The subject  of injecting controlled current into body  tissue comes
  up in sci.electronics.design from time to time. The  body resistance
  is highly variable, so high voltages may be required to  achieve the
  desired current.  This  leads to safety  and  reliability  issues to
  prevent electrocuting the victim as you have described.

  The problem  of  tissue  damage   from  too  much  current  is often
  recognized, and  attempts  are made to limit the  output  to prevent
  damage.

  A recent thread discusses voltage-to-current converters  which could
  be controlled  from  a DAC under control of  software,  or  a simple
  potentiometer for manual adjustment. The thread starts at

    Subject: Bipolar current source for muscle stimulations
    http://tinyurl.com/4ujjh

  The initial proposal uses an op amp with the output  short circuited
  to ground.  I  really  don't like this  approach  due  to  the large
  recovery time needed after the op amp saturates during transients.

  After much discussion, Ian proposed a dramatically simpler approach:

    From: Ian ([email protected])
    Subject: Re: Bipolar current source for muscle stimulations
    http://tinyurl.com/4cbq4

  And a  bit  of  additional refinement  would  indeed  make  this the
  preferred method. I found balanced opposing current sources to be an
  extremely reliable and safe method, and have used them since 1970.

  An example  is  shown  in  Figure  2B  in  my  Data  Recovery patent
  3,810,234. See  the differential bridge made with 2N4209  and 2N5851
  on page 4:

    http://www3.sympatico.ca/add.automation/patents/3810234.htm

  A basic  circuit  to  meet   your  requirement  could  be  made with
  inexpensive NPN's and PNP's for under several dollars in parts cost.

  A simple modification to an ordinary sound card would allow software
  control of  the  current,  and would allow  pulsing  the  current if
  desired.

  Potentiometers from an old monitor could be used for manual control.
  A simple 555 timer could be used if pulsing the current is needed.

  Probably the  power supply would be the most  expensive  item, since
  the required  voltage  depends  on how much  current  you  wanted to
  achieve in  dry  skin.  However, ensuring the  skin  is  damp should
  greatly reduce the supply voltage needed.

  I'm not sure conductive gel might not react with the silver ions.

  Bear in  mind  that  currents above about  5  ma  start  to paralyze
  muscles, and control is lost around 25mA or so. I have more detailed
  info on  the effects of current in humans, but the url is  not handy
  at the  moment.   I'd   definitely   recommed  studying  this aspect
  carefully  and   incorporate   the   needed   controls   to  prevent
  electrocution.

Best,

Mike Monett


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