Here's a link to an FDA report on the effectiveness of giving a lower dose
of Interceptor for preventive. Safeheart dosage is 1/5 the dose amt. of
Interceptor and is effective against heartworms (though at the lower dose it is
not
effective against hookworms, roundworms, etc...) Safeheart is not to my
knowledge marketed in the US, but you can use Interceptor at the Safeheart
dose. For example, a 50lb. dog could be given the 10lb. dose to prevent
heartworms. Unless a dog is also at constant high risk of getting hookworms,
roundworms, and/or whipworms along with the risk of heartworm, then it makes
no
sense to give 5 times the necessary dose. Don't know if CS/EIS is capable of
killing the microfilaria in the bloodstream, which is how heartworm is
'prevented', but it couldn't hurt. On the other hand, black and green walnut
hulls can
be very toxic; personally I wouldn't risk giving those over the 1/5
Interceptor.
Laura H., TX
_http://www.fda.gov/cvm/FOI/1365.htm_ (http://www.fda.gov/cvm/FOI/1365.htm)