These are quotes from the same article, relating to CFS, FMS and magnesium.
http://www.coldcure.com/html/dep.html#codex
Fibromyalgia, Chronic Fatigue Syndrome and Magnesium
Fibromyalgia, (severe muscle cramps or pain in leg, foot, neck,
chest, back, soft tissue) and chronic fatigue syndrome (CFS) appear nearly
always symptoms of moderate magnesium deficiency coupled with excess calcium
accumulation and possibly low potassium. For example, Shealy, et al. showed
in 1992 that 80 percent of more than 200 patients with depression and/or
chronic pain had magnesium serum levels below normal here. Magnesium malate
has a history of use in treating fibromyalgia. Many articles concern low
magnesium levels in chronic fatigue syndrome and low magnesium in
fibromyalgia. Also, there is much interest in potassium problems in CFS.
Although I am quite certain that fibromyalgia is primarily a low magnesium
problem, I now believe that CFS is a low magnesium and low potassium
problem. This seems to be a novel approach to treating CFS, but it may have
much more merit than anyone could have predicted as few as 5 years ago. See
the discussion in this page concerning foods and salts that can be used to
increase potassium here, and do a search generally in this page for
"potassium" to learn about its hazards and benefits. Potassium is the most
prevalent metal inside cells at about 70% of the mineral content of cells,
and plays vital life- and health-sustaining roles. See this page for a
comprehensive discussion of treatments and causes of CFS. As previously
mentioned, magnesium regulates many nerve receptors, such as NMDA or 5-HT3.
When inadequately regulated due to magnesium deficiency, those receptors
cause fibromyalgia pain and increase sleep deprivation, further worsening
magnesium deficiency. Fibromyalgia and chronic fatigue syndrome are often
not diagnosed by internists, rather they conduct multiple expensive tests to
rule out other possibilities. These painful symptoms are always predictive
of major health problems in the future including cardiac trouble and
depression if not treated with ionizable magnesium at about 200 mg three to
four times a day. However, menstrual cramps are symptoms of zinc deficiency,
not magnesium deficiency. Read more in this essay about how calcium toxicity
and magnesium deficiency cause fibromyalgia here, and a bit about the
problem of sleep in fibromyalgia here. Doesn't it seem more reasonable to
you, the patient, to try something nutritional before spending a fortune on
expensive tests? You don't believe me? How about believing a MIT researcher
and his extensive research? If you wait for your doctor to make this
diagnosis, I hope you have plenty of money or really good insurance. On the
other hand, see what one of the best CFS physicians in the world, Dr. Sarah
Myhill in Great Britain does for fatigue here.
Some people are so calcified by calcium-abuse that their joints and back
hurt from laying down, which likely applies to you. As your
magnesium/calcium balance improves over the first year of magnesium
replenishment and calcium depletion, you will likely notice that pain
associated with sleep disappear.
Normally, melatonin concentration is 6 to 12 times higher at night than
during the day. Replenishing night-time melatonin to youthful levels
sometimes results in restoration of youthful sleep patterns.
In depression, high quality sleep is mandatory for recovery, but is often
very difficult to achieve without magnesium and taurine repletion and a low
glycemic diet. Remember that both stress and a high glycemic diet
dramatically lower intracellular magnesium and must be controlled. Had
Weston's discovery of the sedative value of magnesium been fully utilized
over the last 80 years, many problems due to inadequate sleep (in depression
or otherwise), could have been largely avoided. Clearly, 400 - 500 mg of
ionizable magnesium at bedtime induces a natural, pleasant sleep unequaled
in the human experience. On the other hand, lack of sleep is another cause
of magnesium deficiency; probably due to the lowered amounts of growth
hormone secretion, which occurs as result of sleep deprivation. Growth
hormone is responsible for creating a substance known as insulin growth
factor (IGF-1). IGF-1 has been found to have many uses in the body, but is
best known for tissue repair, which occurs primarily during sleep. Lack of
sleep is often found in people with fibromyalgia, which is responsive to
magnesium repletion. Magnesium ions regulate many nerve receptors, such as
NMDA or 5-HT3. When inadequately regulated due to magnesium deficiency,
those receptors cause fibromyalgia pain and increase sleep deprivation,
further worsening magnesium deficiency.
Theanine readily crosses the blood-brain barrier of humans and exerts subtle
changes in biochemistry. An increase in brain alpha waves (resulting in an
increase in wakeful relaxation) has been documented, and the effect has been
compared to getting a massage or taking a hot bath. And, unlike
tranquilizing drugs (including kava-kava, valerian and St. John's wort), it
doesn't interfere with the ability to either think or exercise good
judgement. It does not sedate, as demonstrated by no change in brain theta
waves upon administration. It does not help one doze or fall asleep, unless
the person is excited or hyper. By shutting down the "worry" mode,
L-theanine increases concentration and focuses thought. This is the concept
behind the Japanese tea ceremon
When calcium gets into cells, the cells turn on, whatever "on" is for those
cells. In the case of stress-induced depression and related mental
disorders, the cells are the neuro synaptic cells of the brain discussed in
depth here. When calcium enters a muscle cell, the muscle contracts. If
excessive calcium stays there, the muscle stays contracted and results in
severe pain. The familiar knots in our upper backs and necks are just such
calcified muscles that are stuck in the "on" or contracted position. The
pathological version of this condition is called fibromyalgia where there
are many such knotted muscles.
--
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