Dear Mike,
Type 1 diabetes is considered to be an autoimmune disease in
which T lymphocytes infiltrate the islets of pancreas and destroy the
insulin producing beta cell population. Besides antigen specificity,
the quality of immune reactivity against islet cell antigen(s) is an
important determinant of the beta cell destruction.
Evidence indicates that the function of the gut immune system is
central in the pathogenesis. The role of virus infections in the
pathogenesis of type 1 diabetes has been supported by substantial new
evidence suggesting that enteroviruses may trigger the beta-cell
damaging process in a considerable proportion of people. Ozone
treatment is effective in eliminating enteroviruses.
The latest evidence comes from studies indicating the presence of
viral genome in diabetic patients and from prospective studies
confirming epidemiological risk effect.
Of the dietary putative etiological factors, cow's milk proteins
have received the main attention. Many studies indicate an association
between early exposure to dietary cow's milk proteins and an increased
risk of type 1 diabetes.
Another dietary factor emerging is the deficiency of vitamin D.
Among toxins, N-nitroso compounds are the main candidates.
--
Regards,
Catherine
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