List,
Many members know about big Pharm fraud, but few examples are as
compelling at the L-Tryptophan scam, which I recall very, very well.
BROJON, although being rather uneven in my opinion, has a great piece
which I am pasting below.
THE INSIDER'S STORY OF AN L-TRYPTOPHAN RESEARCHER
A Response To Reader's Requests
I have received a number of letters to the editor asking about which
L-tryptophan is the best and where to buy it. Many readers want to
start using it each morning to maintain their circadian rhythms. For
almost 20 years it has been impossible to purchase L-tryptophan. So
where did I buy my tryptophan for my research for the last 20 years?
During the 1980's when I started my circadian rhythm experiments, I
used the common L-tryptophan found in stores. I soon found there were
two types --one with B6 and one without any B6. I tried several brands
of each and found that the ones with B6 did not work at all in my
experiments for shifting or controlling the circadian rhythms. Thus
proving that B6 prevents tryptophan from getting into the brain. Using
B6 will definitely disrupt your normal circadian rhythms.
I later found that almost all the L-tryptophan in all brands was made
from the same bulk raw product from Japan. The Showa Denko company had
developed a method of using genetically modified bacteria to extract
copious amounts of L-tryptophan from milk. Since the bacteria was
removed and reused, what remained was pure, cheap L-tryptophan. It is
now the same method used for making all the other amino acid products.
In November 1989, the CDC made the false claim that L-tryptophan was
causing a new disease or disorder called Eosinophilia Myagia Syndrome
(EMS). The symptoms of EMS were exactly the same as trichinosis.
Trichinosis is a parasite which comes from eating improperly cooked
pork. My research found that about half of all American's have
contracted the trichinosis parasite. But for most people it is
sub-clinical, meaning most people don't even know that they have
trichinosis. This sub-clinical form of the disease is the primary
reason for most autoimmune disorders such as fibromyagia and chronic
fatique syndrome. The body immune system attacks itself in an attempt
to get rid of the parasite. The disease is caused by microscopic worms
embedding by the millions into your muscles. Then they form a tiny
impenetrable cyst which protects them from medication and from your own
immune system. No effective medication has been found for ridding the
body of trichinosis.
For most people the original symptoms were a slight fever like the flu,
and achy muscles as the trichinella enter the muscles and become
encysted. It takes about a week and later those early symptoms go
away and are forgotten. Those were exactly the same symptoms which
were identified as EMS by the CDC. In the first week after the CDC
alert for EMS, the doctors before reporting EMS needed to perform a
trichinosis test. In the second week after the CDC alert, the
trichinosis test requirement was strangely dropped, so all the usual
hundreds of thousands of cases of trichinosis were then falsely
reported to the CDC as the new tryptophan disorder, EMS.
The CDC also changed the reporting requirement to include: observe the
symptoms and also, secondly interview the patient for having previously
or still using L-tryptophan. Thus, suddenly this became an
L-tryptophan disease. But it wasn't at all. It was just the common
trichinosis. I was using L-tryptophan in my research studies but I
never had any symptoms. Something was very wrong with the CDC story
about EMS and the ban on sales of L-tryptophan.
I suspected then that this was a fraudulent story and I have kept in my
files, several years worth of all the CDC reports and university
research reports into the suspected causes for EMS. The CDC even
blamed Showa Denko for making a contaminated product and forced them
out of business. But NO cause of EMS was ever found and the story was
quietly dropped, but the ban for local drug stores to sell L-tryptophan
has remained. Mysteriously and quietly the ban on sales has been
dropped in the last year and now many small sellers are using the
Internet to push L-tryptophan. Why? What has suddenly changed?
The original reason for banning the sale of L-tryptophan is still a
mystery. I suspected the illegal ban was bought and paid for by Eli
Lilly which made nearly a trillion dollars by selling Prozac, which was
designed to replace L-tryptophan as a means to raise the level of
serotonin in the brain. Of course the reason for the "brain chemical
imbalance" or low level of serotonin in the first place was the
over-abundance of B6 in the diet which eliminates L-tryptophan from the
body. That strange relationship is why I have studied and done
experiments with both L-tryptophan and B6 for the last 20 years.
Right after the sales ban in November 1989, I looked for alternate
sources for L-tryptophan. I did find a source, a company called BIOS
Biochemical, which was continuing to sell L-tryptophan, not for people,
but to farmers who added the product to cattle feed. Since about 10
percent of the protein in cow's or mother's milk is tryptophan, by
adding L-T to the dairy feed, the farmers could increase the milk
output from their cows. Adding $5 worth of tryptophan to the dairy
feed would increase the milk output by about $500 over the life of the
dairy cow. Such a deal for the farmer on such a small investment.
The BIOS Biochemical product was also USP quality so it was certified
for purity and content -- even though the product was clearly marked
"For Veterinary Use Only." Just ignore that. That was to get around
the CDC ban. L-tryptophan from cows milk or mother's milk is exactly
the same. If the CDC wanted to completely ban L-tryptophan they would
have needed to outlaw breast feeding. And that's never going to
happen. Also L-tryptophan, when it was packaged with other amino acids
and vitamins such as B6 was never banned for sale. Is that mysterious
or what?
At that time, BIOS was the only source I found for tryptophan and it
was online in 1990, which was just a few years before the Internet. In
those days, to be online meant you had an account with Compuserve, AOL
or smaller sites such as Mindspring. AOL actually let you create your
own “homepage” or “webpage” which since than has grown from several
hundreds of pages to multiple billions of websites. I have been using
BIOS Biochemicals for 16 years. For cattle feed, the company sells
L-tryptophan in large bags or bulk containers by the multiple pound.
They also sell the powder in 500mg capsules. I had been using 250 to
500mg capsules before 1989. I figured that the cattle farmers are not
stuffing capsules in the mouths of their cattle, so the only purpose of
the capsules must be for human use.
Thus, BIOS must have known that their biggest L-T market was tryptophan
for humans who did not believe the CDC's EMS hoax story. Prior to the
CDC ban, about 30 million Americans had been using L-tryptophan for a
variety of problems, mostly circadian rhythm disorders. Most of these
people were later diagnosed as "brain chemical disorder" and were put
on Eli Lilly's Prozac. Thus Lilly already had a huge ready-made market
for their Prozac. But instead of a 20-cent L-tryptophan capsule each
day, the people were paying $20 or more per day for Prozac -- which
supposedly did the same thing.
Since BIOS has also sold its L-T in large bags since before the 1980's,
I assume that most of all the other small marketers who now sell
L-tryptophan online are simply buying the big bulk bags from BIOS and
then repackaging it into small capsules. Since it costs a lot of money
to get a product USP certified, it seems only natural that all the
smaller tryptophan companies now selling on the Internet are getting
their USP certified product simply by buying the raw product in bulk
from BIOS. What that means is that it doesn't matter which brand or
source you use for USP L-tryptophan -- because they are all the same
-- they all come in bulk from BIOS Biochemicals.
If you search on Google for buying L-tryptophan you will get many pages
for marketers of USP L-tryptophan. Way down on the 4th or 5th page you
find BIOS. The reason is because BIOS doesn't need to advertise their
product. They ARE the source, and everybody else is selling their
product. BIOS doesn't need to compete with its own distributers.
Based on that information, I have been buying directly from the source
for the last 16 years. If you find something better let me know. I
don't work for BIOS, so I am not selling or promoting their product. I
just use it.
And what about the strange mystery of why it has suddenly become so
easy to buy L-tryptophan? Maybe it is just strange coincidence (I
don't believe in strange coincidences), but two years ago the Eli Lilly
international drug patent ran out. Numerous other pharmaceutical
companies are now making generic Prozac, not for $20 per dose, but for
about a dollar a dose. So Prozac is no longer a big profit item. The
Prozac era has come to an end. There is no longer a need to eliminate
the competition from 50 cent L-tryptophan. Since nobody is now pushing
for a ban on L-tryptophan to keep competitors off the market, it has
suddenly become very easy to purchase it, but still it is not being
stocked in stores. So buying online is still the best bet. But that
does explain the mysterious and sudden easing of the ban on
L-tryptophan. Could the 19-year ban on the sales of L-tryptophan be
called a huge billion dollar Big Pharma fraud? You betcha. And
similar such frauds are continuing today.
But if you doctor is still suggesting you use Prozac or Zoloft or any
of the other similar SSRI's consider this. If you take L-tryptophan in
the morning it produces serotonin in the brain, and raises the brain
temperature and wakes you up. If you take L-tryptophan in the evening
it produces melatonin in the brain, which lowers the brain temperature
and induces sleep. This operates the daily cycle of your circadian
rhythms.
If, instead, you take Prozac in the morning, it raises your brain
temperature, and works something like an anti-depressant. But if you
take Prozac with an evening meal, as prescribed by some doctors, it
will still raise your brain temperature and keep you awake all night
long. One of the most common reported side-effects of Prozac or the
other SSRI's is insomnia or circadian rhythm disorders. It only works
as an anti-depressant if you take it first thing in the morning. But
if instead, you take L-tryptophan at any time of day, it automatically
converts to serotonin or melatonin depending on the time of day when
you take it. It works automatically to run your circadian rhythms, you
can't overdose and there are no side-effects such as insomnia. But for
“Tryptophan Pumping” is still works best if you take it first thing in
the morning. That's how you get optimum and quickest results.
If you want to do your own circadian rhythm experiments, go here:
BIOS Biochemicals
www.biochemicals.com
If you find this information is valuable, post a copy of this to the
Internet and let everyone know about it. Also tell your friends that
they can sign up for the BroJon Digest to get the latest research about
circadian rhythms, as it is published. Or go to the BroJon Gazette to
read all the stories in the “B6 Bomber” series.
Marshall Smith
Editor, Brother Jonathan Gazette
[email protected]
Click here to find the live links to the full stories in the Gazette -
http://www.brojon.com
KBB
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