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From: Cajun Mike
To: LeRoy Carlson ; LeRoy Combs
Cc: Zena Mungovan
Sent: Tuesday, March 09, 2010 10:34 AM
Subject: Fw: CANCER CODE IS CRACKED
CajunMike & Zena Mungovan
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--- On Mon, 3/8/10, J & J McNeil <[email protected]> wrote:
From: J & J McNeil <[email protected]>
Subject: CANCER CODE IS CRACKED
To: "Cajun Mike Mungovan 08" <[email protected]>
Date: Monday, March 8, 2010, 4:01 AM
CANCER CODE IS CRACKED
Researchers believe they have succeeded in halting the spread of
advanced cancer
Sunday March 7,2010
By Lucy Johnston
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SCIENTISTS believe they have made a major breakthrough in cancer
treatment after cracking the “code” behind the disease.
They have discovered the body’s immune system can kill cancer cells
within a window occurring every 12 to 14 days.
By giving low-dose treatment at exactly the right time, researchers
believe they have, against the odds, succeeded in halting the spread of
advanced cancer.
Professor Michael Quinn has led the trial in patients with advanced
ovarian cancer and suggests it could signal the most exciting development since
the introduction of chemotherapy in the Fifties.
While he points out that it is still a theory, he said: “This is
astonishing and could infl uence the treatment of all solid tumours in the
future. We hope it will revolutionise the treatment of cancer.” Professor Quinn
and his team reviewed 63 papers involving more than 1,200 patients since 2000.
They discovered that sufferers had about a 1-in-12 chance of responding
to chemotherapy. During further studies they found the body has a fortnightly
immune cycle during which it “switches on and off”.
When the immune system turns off, it releases “inhibitory cells” which
prevent it fighting disease, including cancer.
Professor Quinn and his team in Melbourne, Australia, target
chemotherapy when the immune system is not working to knock out “inhibitory
cells”, dramatically improving patients’ chances of recovery.
The treatment is in pill form and patients avoid almost all the
debilitating chemotherapy side effects.
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Professor Quinn, originally from Glasgow, said: “Everyone, including
non-cancer patients, has an immune cycle which fluctuates every 12 to 14 days.
“That’s why if someone in the family comes in with a cough or cold,
only some members of the family will develop it. The immune system also attacks
cancer cells, which is why we need to give chemotherapy on the right day."
“The concept is sensational. If you can treat people at the right time
it could dramatically improve their chance of a successful outcome. The
research is still in its early stages, however if we are proved right this
method of treatment could be applied to all cancers and in fact all diseases.”
Since last year Professor Quinn and his team at Royal Women’s Hospital
and Monash University, Melbourne, have given the therapy to seven women. Their
advanced, recurrent ovarian cancer is almost impossible to treat successfully.
Several responded positively and their tumours have stopped growing. Professor
Quinn added: “These are very, very promising results.”
One patient, Melissa Campbell, went to her doctor four years ago with
back pain and a bloated stomach, and was diagnosed with advanced ovarian cancer.
The disease recurred twice, and she has endured surgery, chemotherapy
and radiotherapy, as well as severe side effects from another experimental drug.
The 44-year-old said the new treatment had been a totally different
experience: “It’s keeping it under control, and fingers crossed it will get rid
of it down the track. It’s so much easier compared with the other times.”
The treatment is a pill taken for a few days every fortnight rather
than the patient being attached to a drip in hospital. Blood tests are also
carried out every two days to assess the immune system.
Preliminary work is now underway to use the same methods to treat
patients with skin cancer. Professor Peter Johnson, Cancer Research UK’s chief
clinician, welcomed the news: “We know the immune system may be influential in
treating many cancers.
“Any research that helps our understanding may hold promise for the
future.”
