Some popular ones:

http://folding.stanford.edu/ for protein folding research to cure diseases.
http://www.mersenne.org/ for prime number search to improve cryptography.
http://setiathome.berkeley.edu/ for pattern searching satellite data
in the search for extra-terrestrial intelligence

There's a big (actually, huge) list here:
http://en.wikipedia.org/wiki/List_of_distributed_computing_projects

If the link domain ends in .edu then they're from an American
university and are probably safe.

2009/2/16 [email protected] <[email protected]>:
> This may not be a purely Linux question but I have a feeling that someone
> would have some advice.
> My windows computer often spends a lot of time in idleness,
> Does anybody know of a distributed computing screensaver so that I can put
> my computers idle moments to work for the good of all humanity.
> I am particually interested in anything to do with curing deseases, bio
> chemistry, machines / engineering
> I am scared of downloading troajaned software though
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