Can you try with a different graphics card to test? You can buy a replacement 
then send it back if it doesn’t resolve the issue.

I believe the new MacMinis are all soldered PCIe storage these days, they don’t 
have a SATA port anymore. You could connect your SSD via a USB3 enclosure and 
it would be almost the same speed as in your MacPro.
_      
Regards
Sam Mullen

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[email protected] <mailto:[email protected]>
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> On 15 Aug 2020, at 22:45, 'Jason Davies' via Sussex Mac User Group 
> <[email protected]> wrote:
> 
> Hi smuggers,
> 
> I've never seen a problem like this. My old Mac Pro, with an upgraded 
> graphics card that supports Metal in Mojave has suddenly started failing to 
> launch apps but only some apps. It started on Friday when I was in the middle 
> of doing stuff, and it was behaving normally, then suddenly it wasn't.
> 
> Eg it starts up normally but then apps that normally take a few seconds take 
> about 20 minutes to launch (no exaggeration). Once launched, they might or 
> might not work normally. Virtually every app does this but not all - eg 
> Activity Monitor behaves completely normally, starts up in a few seconds. 
> Safari, which launches after about 3 or 4 minutes, quits in a second when I 
> tell it to, but other apps get stuck and never quit. The Finder is meanwhile 
> normally responsive, eg copying a 6 gig file to a USB drive in a couple of 
> minutes.
> 
> I've run an ancient copy of Rember (RAM checker), and done the Crucial 
> 'garbage disposal' thing by starting up in Target Disk Mode and leaving it 
> for 8 hours.
> 
> What makes it difficult is that because of the new graphics card, that let it 
> run Mojave, does not display the usual 'hold down a key at start-up' options 
> such as hardware test or selecting start-up disk. Holding down Shift for Safe 
> Mode seemed to just make it hang indefinitely forcing a hard shutdown.
> 
> The start up is an SSD connected via PCIE card. So tomorrow I'm going to try 
> removing each of the 8 gig RAM sticks and seeing if that eliminates it, then 
> connecting the SSD into one of the internal bays (it was a bit slow generally 
> doing this but would point at the PCIE card). I'll also try to create a 
> Mojave start-up but annoyingly, despite the upgraded graphics card, trying to 
> run the Mojave combo refuses to launch as it thinks my graphics card doesn't 
> support Mojave.
> 
> All of which makes me think maybe it's time to replace it if I can't work 
> this out. I can only afford a Mac Mini but the entry level has a puny 256 
> internal start-up. How hard is it to swap that out for my existing 2.5" SSD 
> (if possible at all?)
> 
> If anyone can think of anything else to try, please let me know. I've run 
> Disk Utility and am considering if I can erase and restore the SDD as HFS+ so 
> that diskwarrior will play nice with it. I've also removed and re-seated the 
> RAM after carefully vacuuming out the internals.
> 
> Cheers,
> Jason
> 
> 
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