I don't know if this is helpful or not...but I
remember her saying something about it being in her
spine.

Laurie


Ferraro Fighting Multiple Myeloma  
 
Was diagnosed in 1998  
 
  
 
 
 
 Related Resources  
� Internet links on multiple myeloma
 
 
 
 
 
 
 Elsewhere on the Web  
� U.S. Congress Biography: Geraldine Ferraro
� CNN.com: Ferraro using Thalidomide against blood
cancer
 
 
 
 
Mary Kugler, MSN, RN,C
Guide to Rare/Orphan Diseases
June 20, 2001

How it began
In 1998, Geraldine Ferraro made a bid for a seat in
the United States Senate, but lost. That December,
when she went for her annual physical, her doctor
noticed something irregular in her white blood cell
count. Testing showed she was in the early stages of
plasma cell cancer. "When he said 'multiple myeloma,'
I said, 'What's that?'," Ms. Ferraro recalled in an
interview with The New York Times. What she learned
was that the cancerous plasma cells in the blood can
form a tumor in the bone marrow, called myeloma;
tumors in several sites is termed multiple myeloma. 

The statistics
Like most of the 14,000 people in the United States
diagnosed with multiple myeloma each year, Ms. Ferraro
had no history of the disease in her family, and no
apparent risk factors. No specific cause for the
disease has been found, although some possible
associations with chemical and radiation exposure have
been suggested. Generally, multiple myeloma seems to
start in people between the ages of 65 and 70. It is
the second most prevalent blood cancer and represents
1% of all cancers, and 2% of all cancer deaths.
African-Americans and Native Pacific Islanders have
the highest rates of the disease, and Asians the
lowest. 

Treatment
There is no cure for multiple myeloma. About half of
the people diagnosed with the disease die within 5
years. Multiple myeloma suppresses the immune system,
leads to anemia, nerve failure, infections, and bone
fractures. 

The standard treatment for the disease has always been
chemotherapy, followed by bone marrow transplant,
radiation, and more chemotherapy. All of this
difficult treatment only adds two or three years to
the person's life. 

Thalidomide
In 1998, cancer researchers started looking at
antiangiogenesis--preventing the growth of tumors by
cutting off the growth of the blood vessels that feed
the tumor. One drug, Thalidomide, seemed to be
promising for this. Thalidomide had a notorious past.
The drug, when used for morning sickness in pregnant
women in the 1950s and 1960s, caused thousands of
babies to be born with severe birth defects. However,
when used against cancer, it seems to be very
effective. 

Dr. Ken Anderson, Ms. Ferraro's physician, stated in a
news conference on June 19 that Thalidomide "has the
ability not only to kill the tumor cell directly, but
also to act in the neighborhood or in the bone marrow
to make it impossible for the myeloma cell to grow and
survive there." 

For people with multiple myeloma, Thalidomide seems to
work when other therapies fail. In about 80% of cases,
the drug drastically reduces the presence of cancer
cells in the blood. Ms. Ferraro credits Thalidomide,
which she has been taking for two years, with helping
her stay in remission and avoid chemotherapy. "I look
great, and I feel great, and it's what early diagnosis
and research can do," she stated in that same New York
Times interview. 

Ms. Ferraro will testify about her illness and its
treatment at a Senate hearing on Thursday, June 21, to
help promote funding for research. "For people like
Geraldine and myself, we are buying time," said Kathy
Giusti, president of the Multiple Myeloma Research
Foundation and a myeloma patient, in a CNN interview.
"I think that is why she has gone public. We need
Congress' help. She knows that this will make a
difference in getting this funding." 

Information for this article was taken from:
- Dwyer, Jim. "Ferraro is battling blood cancer with a
potent ally: Thalidomide." The New York Times,
6/19/01. Available online.
- "Ferraro using thalidomide against blood cancer,"
CNN.com 6/19/01. Available online.
- Multiple Myeloma Research Foundation. "Myeloma
Basics: The Statistics." Available online.

 


=====
I wanted a perfect ending... Now, I've learned, the hard way, that some poems don't 
rhyme, and some stories don't have a clear beginning, middle, and end. Life is about 
not knowing, having to change, taking the moment, and making the best of it, without 
knowing what's going to happen next. Delicious ambiguity. 
--Gilda Radner

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