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From: PlusNews <[email protected]>
Date: Wed, Jul 25, 2012 at 11:01 AM
Subject: HIV/AIDS: New investment in point-of-care evaluation
To: Elisabeth Janaina <[email protected]>


HIV/AIDS: New investment in point-of-care evaluation

WASHINGTON DC, 25 July 2012 (PLUSNEWS) - International medicines
financing mechanism UNITAID [ http://www.unitaid.eu/ ] will invest
more than US$140 million to evaluate point-of-care HIV diagnostic and
monitoring technology in seven African countries.

New technology could help put more people living with HIV on treatment
faster and improve care, UNITAID partners said at the international
AIDS conference in Washington DC.

Point-of-care (PoC) technology provides health workers with access to
complicated test results at the clinic level, but can also change how
patients use the health system - not always for the better. [
Point-of-care: 
ttp://www.plusnews.org/Report/90868/MOZAMBIQUE-Technology-revolution-hits-HIV-testing-and-treatment
] The evaluation will investigate what new PoC technology will mean
for patients and health systems.

UNITAID's money - part of a three-year grant - will go towards
field-testing new PoC technology to diagnose babies born to
HIV-positive mums early, and monitor HIV viral loads (the amount of
virus in the blood) and CD4 counts (which measure the immune system's
strength).

The new technologies will be rolled out in projects run by the UN
Children's Fund (UNICEF), the Clinton Health Access Initiative, and
medical humanitarian organization Médecins Sans Frontičres (MSF).

Most HIV tests only detect the presence of HIV antibodies - proteins
produced by the body in response to HIV infection - and although
babies born to HIV-positive mums inherit antibodies, they are not
necessarily for HIV. Special polymerase chain reaction (PCR) tests are
needed look for the actual virus, not the antibodies, to diagnose HIV
in infants.

Blood for these tests can be collected at clinics, but PCR tests and
those to determine CD4 counts and viral loads are usually only
available at district laboratories. Clinics often wait weeks to get
the results, delaying treatment for patients and increasing the
likelihood that they will be lost to follow-up because they lose
interest in getting treatment.

The first step to treatment

Whether or not people access HIV treatment depends on how easy it is
to get the tests and the results, according to UNITAID Executive
Director Denis Broun.

"While we've made progress in reducing life-saving ARV prices for
low-income countries, access to these medicines has been stymied by
limited availability of diagnostics," he told IRIN/PlusNews. "Until we
bridge this access gap for diagnostic technologies, it will be
impossible to really turn the tide on HIV in low-income countries."

Viral load testing also plays a part in allowing healthcare providers
to better identify drug resistance in HIV patients, so doctors and
nurses can switch patients to second- or third-line drugs when their
current treatment no longer works. Importantly, it also decreases the
chance that healthcare providers will switch patients to these more
costly regimens unnecessarily, MSF said.

Research published in British medical journal, The Lancet, and
released at the international AIDS conference in Washington, shows a
rise in drug-resistant HIV in sub-Saharan Africa. Rates of drug
resistance are increasing the fastest in East Africa, where about
seven percent of all HIV patients have some form of drug resistance -
double the proportion of patients with similar resistance in southern
Africa. [ Research:
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2812%2961188-X/fulltext
]

kn/he[END]

This report online: http://www.plusnews.org/report.aspx?reportID=95945



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