I forgot to mention the mzxml files for this run ranged from 15-25 mb.
And I don't know the mass spec used because the spectrum I run are
from a database of other people's mass spectra.

And sorry I forgot to start a new thread,
Kris

On Feb 20, 11:11 am, Kris <[email protected]> wrote:
> Hi Natalie,
>
> I'm using mzxml files that I got from fromwww.peptideatlas.org/repository.
> The one I just ran was PAe000144, using the PAe000144_414_sequest
> params file.
>
> I ran a database search on the last 6 mzxml files. The output files
> says they are Unreadable. The end of the output lines says that it's
> skipping 243489 lines of output, so it is getting output.My main
> concern is that at the end of the output lines, it says:
> "SequestParams: error opening 043005_900c/sequest.params
>
> command "C:\Inetpub\tpp-bin\Out2XML.exe 043005_900c 1" failed:
> Operation not permitted
>
> Command Successful".
>
> It says at the top that I ran this command:
>  run_in d:/Inetpub/wwwroot/ISB/data/PAe000144_mzXML_200709080112;
> runsearch -pd:/Inetpub/wwwroot/ISB/data/PAe000144_mzXML_200709080112/
> PAe000144_414_sequest.params -P15 043005_060a.mzXML
>
> This is wrong because I know I ran this command on all these mzxml
> files. The commands did not load back correctly after updating the
> page.
>  Here is exactly what tthe output files say:
>     * d:/Inetpub/wwwroot/ISB/data/
> PAe000144_mzXML_200709080112/043005_060a.pep.xml [ Unreadable! ]
>     * d:/Inetpub/wwwroot/ISB/data/
> PAe000144_mzXML_200709080112/043005_060b.pep.xml [ Unreadable! ]
>     * d:/Inetpub/wwwroot/ISB/data/
> PAe000144_mzXML_200709080112/043005_060c.pep.xml [ Unreadable! ]
>     * d:/Inetpub/wwwroot/ISB/data/
> PAe000144_mzXML_200709080112/043005_900a.pep.xml [ Unreadable! ]
>     * d:/Inetpub/wwwroot/ISB/data/
> PAe000144_mzXML_200709080112/043005_900b.pep.xml [ Unreadable! ]
>     * d:/Inetpub/wwwroot/ISB/data/
> PAe000144_mzXML_200709080112/043005_900c.pep.xml [ Unreadable! ]
>
> And the last line of the output say:
> ...skipping 243489 lines of output...
>
>   8.   8 /  8          0 2827.07162  0.2661  0.6742    66.6   9/92
> YGL090W_id3058                K.ISNQSVIKMEDDDFDDFQFFGLSK.R
>   9.   9 / 55          0 2826.19648  0.2720  0.6688    40.7   7/96
> YKR079C_id1787                R.FDTPLSRGTSMCKSQEEPLNTIIEK.D
>  10.  10 /  3          0 2827.09756  0.2832  0.6585    91.5  10/96
> YLR127C_id4117                K.ALLSLVDTLHDSDINQDTNITKRDK.N
>
>  38.  38 /  1          0 2826.15561  0.4631  0.4932    99.1  10/88
> YBR136W_id340                 K.KEDVRQDNQYMQFATTM#DFLLSK.D
>
>   1.          0  YOL138C_id5498
>   2.          0  YJR130C_id3891
>   3.          0  YKL105C_id1588
>
> Total search time:   11 secs for 32 files
> Average search time: 0.34 secs
>
> Out2XML 043005_900c 1
> params file here: 043005_900c/sequest.params
> SequestParams: error opening 043005_900c/sequest.params
>
> command "C:\Inetpub\tpp-bin\Out2XML.exe 043005_900c 1" failed:
> Operation not permitted
>
> Command Successful
>
> On Feb 18, 8:22 pm, Natalie Tasman <[email protected]> wrote:
>
> > Hi Kris,
>
> > I'm glad that 4.1.1 on Windows with Apache has installed and is at  
> > least somewhat working for you.
>
> > I assume that you're using the TPP web interface (Petunia).  When a  
> > process is running, you'll see an option to refresh the page and see  
> > the command's current output.  Please copy and paste those command  
> > outputs.  It would be great if you would post back in two separate  
> > threads (with different subjects) for each issue, so that we can keep  
> > track of what's going on.
>
> > Also, if you can give specifics about the type of instrument your  
> > using and the size of the mzXML files used in your runs, that would be  
> > useful.
>
> > Best,
>
> > Natalie
>
> > On Feb 18, 2009, at 4:39 PM, Kris wrote:
>
> > > Hi,
>
> > > I am NOT running TPP off of IIS. TPP will NOT work at all off of IIS.
> > > I have installed TPP 4.1 rev 1 using Apache on a different port.
>
> > > So, TPP should run the way it normally runs.
>
> > > However, I have found multiple issues.
>
> > > First, I will run SEQUEST through TPP using database search. On the
> > > 7th or 8th mzxml file I run, it will throw sequest errors that say
> > > Out2XML failed on the file using sequest.params
> > > This is not the params file I specified.
>
> > > I can try to copy the exact error for you, but I don't have the error
> > > message saved yet.
>
> > > The main issue is that peptide prophet does not work.
>
> > > I will run peptide prophet through analyze peptide and it gets stuck
> > > on the run PepxmlViewer command. There is an INDEX file that
> > > continuously gets bigger and bigger, but the command never finishes.
>
> > > Let me know what error messages I can submit to help you resolve this
> > > issue.
>
> > > -Kris
>
> > > On Feb 17, 12:39 pm, Natalie Tasman <[email protected]>
> > > wrote:
> > >> Hi Kris,
>
> > >> No one has been able to solve your specific program because no one  
> > >> has
> > >> tried the exact setup that you have, which is trying to run Thermo's
> > >> Proteomics Browser Suite, requiring the TPP to use the unsupported  
> > >> IIS
> > >> webserver.  As you've found, the TPP can work with IIS, but we're not
> > >> able to actively support this configuration.
>
> > >> I would recommend that you simplify the situation and install the  
> > >> TPP,
> > >> with the default Apache webserver, on a separate computer.  Even if
> > >> it's an older machine you'll at least be able to isolate the issues
> > >> that you're experiencing.
>
> > >> Please let us know specifically what issues you've found with the
> > >> uninstaller.  By default, the TPP won't delete its data directories.
>
> > >> Best wishes,
>
> > >> Natalie
>
> > >> On Mon, Feb 16, 2009 at 11:53 AM, Kris <[email protected]> wrote:
>
> > >>> Hi,
>
> > >>> I've posted many times, but I still haven't gotten my issues  
> > >>> resolved.
> > >>> I have the Proteomics Browser Suite from Thermo on IIS on port 80 of
> > >>> my computer.
>
> > >>> I have tried the most recent version of TPP (4.1 revision 1) with
> > >>> Apache Webserver on port 8888, and pepxmlviewer was not working  
> > >>> and I
> > >>> was getting random errors where it was saying cannot find parameters
> > >>> file sequest.params. But the parameters file I was using was not  
> > >>> named
> > >>> sequest.params.
>
> > >>> I tried TPP 4.0 revision 2 on apache webserver 8888, but I was  
> > >>> getting
> > >>> sequest27.exe errors when I would run database search.
>
> > >>> I tried running tpp on the IIS server already installed on port 80,
> > >>> but I the following errors on log in:
> > >>> Error Found!
> > >>> MD5_GEN:65280: A fatal error has been encountered.
> > >>> Error Found!
> > >>> NOLOGFILE: Cannot open /tmp/tpp_web.log for writing: Permission
> > >>> denied.
>
> > >>> Let me know if anyone has any suggestions for a stable windows  
> > >>> version
> > >>> of tpp, how to configure it so it works with IIS or on a apache on
> > >>> port 8888.
>
> > >>> I'm also concerned that the uninstalls are not good enough because  
> > >>> it
> > >>> does not seem that all of the files are being deleted. If anyone has
> > >>> any comments on incomplete uninstalls messing up new installations,
> > >>> let me know.
>
> > >>> -Kris
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