Hi David,

The patch works beautifully. Thanks for the fix.

Scott

On Wed, Aug 5, 2009 at 9:24 AM, David Shteynberg <
[email protected]> wrote:

> Hi Scott,
>
> I just checked in a fix to this error in SVN.  The problem was the spectrum
> names were getting extra whitespace at the end in the .tandem files, which
> were being propagated to the pepXML.  The workaround that I committed trims
> any extra whitespace surrounding the spectrum name.  The fix is fairly
> benign and I have verified that it works on your data.  Please give it a
> test and report back any issues.
>
> Thanks,
> -David
>
>
>
>
> On Wed, Jul 29, 2009 at 12:04 PM, Natalie Tasman <
> [email protected]> wrote:
>
>>
>> Hi Scott,
>>
>> Thanks for your feedback and I'm glad David is taking a look.  I just
>> want to remind everyone that svn trunk (which you're working with) is
>> development code.  If you want stable results stick with the official
>> releases.
>>
>> -Natalie
>>
>>
>> On Tue, Jul 28, 2009 at 6:35 PM, Scott
>> Stansfield<[email protected]> wrote:
>> >
>> > Hi All,
>> >
>> > I've just my updated TPP (version 4.4) from the svn last night,
>> > unfortunately when I run xinteract on my sets of TANDEM search results
>> > "0" is returned for all peptide prophet probabilities for all
>> > spectra.  What's upsetting is it worked in the last version I had (TPP
>> > 4.2.1), peptide prophet reports the models and the graphs for each
>> > charge model are saved in the directory. Does anyone know where this
>> > problem could have arisen?
>> >
>> > Cheers,
>> >
>> > Scott.
>> >
>> > I run xinteract on my files like this:
>> >
>> >>xinteract -OdP -dREV -p0 -eT -E20090409_1a_n1_v2
>> -N/data/tpp/data/processing/stansfie/20090409_1a_n1_v2/TANDEM.interact.pep.xml
>> *.TANDEM.pep.xml
>> >
>> > bits of the TANDEM.interact.pep.xml output look like this:
>> >
>> > ...cropped... (there's a model)
>> >
>> > <roc_data_point min_prob="0.99" sensitivity="0.8941" error="0.0008"
>> > num_corr="1501" num_incorr="1"/>
>> > <roc_data_point min_prob="0.98" sensitivity="0.9298" error="0.0013"
>> > num_corr="1561" num_incorr="2"/>
>> > <roc_data_point min_prob="0.95" sensitivity="0.9651" error="0.0024"
>> > num_corr="1620" num_incorr="4"/>
>> > <roc_data_point min_prob="0.90" sensitivity="0.9835" error="0.0036"
>> > num_corr="1651" num_incorr="6"/>
>> >
>> > ...cropped...(this should be better than zero since it's the largest
>> > hyperscore in the dataset)
>> >
>> > </search_hit>
>> > </search_result>
>> > </spectrum_query>
>> > <spectrum_query spectrum="20090409_1a_n1_K4-AMG_C10.01455.01455.3"
>> > start_scan="95" end_scan="95" precursor_neutral_mass="2209.9282"
>> > assumed_charge="3" index="1837" retention_time_sec="96.952"
>> > experiment_label="20090409_1a_n1_v2">
>> > <search_result>
>> > <search_hit hit_rank="1" peptide="LGEHNIDVLEGNEQFINAAK"
>> > peptide_prev_aa="R" peptide_next_aa="I" protein="sp|TRYP_PIG|"
>> > num_tot_proteins="3" num_matched_ions="25" tot_num_ions="76"
>> > calc_neutral_pep_mass="2210.0967" massdiff="-0.169" num_tol_term="2"
>> > num_missed_cleavages="0" is_rejected="0">
>> > <alternative_protein protein="sp|TRYP_PIG|" num_tol_term="2"
>> > peptide_prev_aa="R" peptide_next_aa="I"/>
>> > <alternative_protein protein="sp|TRYP_PIG|" num_tol_term="2"
>> > peptide_prev_aa="R" peptide_next_aa="I"/>
>> > <search_score name="hyperscore" value="977"/>
>> > <search_score name="nextscore" value="412"/>
>> > <search_score name="bscore" value="2"/>
>> > <search_score name="yscore" value="2"/>
>> > <search_score name="expect" value="0.0023"/>
>> > <analysis_result analysis="peptideprophet">
>> > <peptideprophet_result probability="0" all_ntt_prob="(0,0,0)"
>> > analysis="none"/>
>> > </analysis_result>
>> > </search_hit>
>> >
>> > ...cropped...
>> >
>> > >
>> >
>>
>>
>>
>
> >
>

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