Thanks Matt. It was my assumption that 32bit apps generally have no
problem running on Vista. I guess the issue is they cannot take
advantage of the additional processing bandwidth (?).

Memory limitations on 32 bit platforms appears to be 4Gb per
processor. Is this a wrong assumption?  The duo core chips can take no
more than 8Gb DDR DIMMS, whereas Xeons can go way higher, but If it is
a 32bit application, does the Xeon access all of the memory available
to the quad processors while running that 32bit app? In other words,
would you have to have more than 16 Gb of memory on a Xeon to get
similar performance to a duo core with 8Mb? Those larger memory
architectures get pricey fast (though I guess the xeons have bigger L2
cache as well).

Memory seems to be an important consideration in getting faster search
times, but can 32bit applications actually utilize more than 4Gb of
that 8Gb of memory? If not, then it seems that You have to go Xeon
with more than 16Mb of memory to get faster searches (and similar Xeon
clock speeds are more pricey than the same speeds on the duo core
chips).

I just don't want to make a stupid mistake.

On Sep 3, 11:37 am, Matthew Chambers <[email protected]>
wrote:
> Speaking for ProteoWizard, I run Vista 64-bit at home and the 32-bit
> binaries work fine. I haven't dared to compile the 64-bit binaries
> because they wouldn't work with the vendor DLLs anyway. I suspect TPP's
> 32-bit binaries will work fine as well.
>
> -Matt
>
> AndrewK wrote:
> > I don't see hardware or OS limitations for the Windows version(s) of
> > SPCtools. I'll be using Extract_MSN (as well as ReAdW), and am
> > ordering a computer for this platform.
>
> > Is Vista 64bit OK?
>
> > Andrew
> > UMKC-Proteomics
> > Kansas City

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