I am using OUT2XML.exe for our purpose. So Windows binary would be fine.

Thanks,
~Nikhil

On Wed, Sep 9, 2009 at 1:32 PM, Jimmy Eng <[email protected]> wrote:

>
> Thanks for reminding me.  I was on vacation when I sent that email
> last week and forgot all about it.  But I'm back and will look into
> the Out2XML code right now.  Assuming (big assumption) I can get it
> modified today, would you need a Windows binary or are you using the
> TPP tools on a different platform?
>
> - Jimmy
>
> On Wed, Sep 9, 2009 at 10:23 AM, Nikhil Garge<[email protected]>
> wrote:
> > Hello Mr. Eng,
> >
> > Did you get chance to fix the OUT2XML output for SEQUEST outfiles with
> > "duplicate_references"? Actually the current data I have has few
> experiments
> > with duplicate refrences options used and hence would be good if an XML
> file
> > can be created for such experiments.
> >
> > Please let me know.
> >
> > Thanks and regards,
> > ~Nikhil Garge
> > Biostatistics analyst
> > RTI International
> > Durham NC 27709
> > Email: [email protected]
> > Phone: 919-541-5902
> >
> >
> >
> > On Fri, Sep 4, 2009 at 10:18 PM, Jimmy Eng <[email protected]> wrote:
> >>
> >> There's a search parameter (print_duplicate_references) which defines
> >> printing out the additional protein references that a peptide matches.
> >>  Should be a straightforward fix to Out2XML to handle these files
> >> (which I'll look at next week when I get back if no one has updated
> >> the program by that time).  To avoid the problem in the near term, set
> >> that parameter to 0 (which equals false).
> >>
> >>
> >> On Fri, Sep 4, 2009 at 12:36 PM, nik<[email protected]> wrote:
> >> >
> >> > Hello,
> >> >
> >> > Some SEQUEST *.out files have uncommon format. In these files there
> >> > are multiple lines representing the first hit. The second hit
> >> > information starts after several lines of first hit information. For
> >> > such OUT files get following XML output (below SEQUEST output
> >> > example). The second hit information in XML output is wrong.
> >> >
> >> > Did you come across such OUT files (and see mistake in XML output )?
> >> > Please help.
> >> >
> >> > SEQUEST OUT Example: ****************
> >> >
> >> > 2009_0813_04.11113.11113.1.out
> >> >  SEQUEST v.28 (rev. 12), (c) 1998-2007
> >> >  Molecular Biotechnology, Univ. of Washington, J.Eng/S.Morgan/J.Yates
> >> >  Licensed to Thermo Fisher Scientific Inc.
> >> >  08/28/2009, 08:46 PM, 0.0 sec. on EIDOTHEA
> >> >  (M+H)+ mass = 605.89500 ~ 1.5000 (+1), fragment tol = 2.0000, MONO/
> >> > MONO
> >> >  total inten = 2611.6, lowest Sp = 43.9, # matched peptides = 2351
> >> >  # amino acids = 28842, # proteins = 75484, F:\Databases
> >> > \Human_NCBI_36_3_Rev.fasta, F:\Databases\Human_NCBI_36_3_Rev.fasta.hdr
> >> >  ion series nABY ABCDVWXYZ: 0 1 1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0
> >> >  display top 20/5, ion % = 0.0, CODE = 101040
> >> >  C=160.03064 M=147.03540  Enzyme:Trypsin(KR) (2)
> >> >
> >> >  #   Rank/Sp      Id#     (M+H)+    deltCn   XCorr    Sp    Ions
> >> > Reference                                 Peptide
> >> >  ---  --------  --------  --------   ------  ------   -----  ----
> >> > ---------                                 -------
> >> >  1.   1 /  6      10663  607.26819  0.0000  0.2996    43.9   5/ 8  gi|
> >> > 91206454|ref|NP_001035146.1|      +12  -.SSEER.-
> >> >                   22105  gi|149944548|ref|NP_055990.1| neur
> >> >                   31637  gi|91206456|ref|NP_690002.2| hypot
> >> >                   31801  gi|116812577|ref|NP_057103.2| LUC7
> >> >                   34015  gi|169167854|ref|XP_001723047.1| P
> >> >                   34369  gi|169178513|ref|XP_001715551.1| P
> >> >                   39319  gi|157364943|ref|NP_005232.2| ecot
> >> >                   49195  gi|157364945|ref|NP_001098548.2| e
> >> >                   55866  Rev_gi|116008442|ref|NP_055885.3|
> >> >                   56885  gi|63055053|ref|NP_055575.2| TatD
> >> >                   60751  gi|113416552|ref|XP_001128002.1| P
> >> >  2.   2 /  6      29973  606.32056  0.0226  0.2928    43.9   5/ 8  gi|
> >> > 156119625|ref|NP_002206.2|        +3   -.SSEKR.-
> >> >                   45044  Rev_gi|10863967|ref|NP_066993.1| h
> >> >                   55866  Rev_gi|116008442|ref|NP_055885.3|
> >> >                   55866  Rev_gi|116008442|ref|NP_055885.3|
> >> >  3.   3 /  6      31801  606.32056  0.0501  0.2846    43.9   5/ 8  gi|
> >> > 116812577|ref|NP_057103.2|             -.SSKER.-
> >> >  ...
> >> > **************************************
> >> >
> >> > XML output for above SEQUEST OUT:
> >> > **********************
> >> >
> >> > <spectrum_query spectrum="2009_0813_04.11113.11113.1"
> >> > start_scan="11113" end_scan="11113" precursor_neutral_mass="604.8877"
> >> > assumed_charge="1" index="1123">
> >> >    <search_result>
> >> >      <search_hit hit_rank="1" peptide="SSEER" peptide_prev_aa="-"
> >> > peptide_next_aa="-" protein="gi|91206454|ref|NP_001035146.1|"
> >> > num_tot_proteins="13" num_matched_ions="5" tot_num_ions="8"
> >> > calc_neutral_pep_mass="606.2609" massdiff="-1.373190" num_tol_term="2"
> >> > num_missed_cleavages="0" is_rejected="0">
> >> >        <search_score name="xcorr" value="0.300"/>
> >> >        <search_score name="deltacn" value="0.050"/>
> >> >        <search_score name="deltacnstar" value="0.000"/>
> >> >        <search_score name="spscore" value="43.9"/>
> >> >        <search_score name="sprank" value="6"/>
> >> >      </search_hit>
> >> >      <search_hit hit_rank="2" peptide="SSEER" peptide_prev_aa="
> >> > is_rejected="0">
> >> >        <search_score name="xcorr" value="0.000"/>
> >> >        <search_score name="deltacn" value="0.050"/>
> >> >        <search_score name="deltacnstar" value="0.000"/>
> >> >        <search_score name="spscore" value="0.0"/>
> >> >        <search_score name="sprank" value="0"/>
> >> >      </search_hit>
> >> >    </search_result>
> >> >  </spectrum_query>
> >> >
> >> > ***********************************************
> >> >
> >> > Thanks,
> >> > ~Nikhil
> >> >
> >> > >
> >> >
> >>
> >> >>
> >
>
> >
>

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