Luis,

we have deployed on our Linux cluster TPP version 4.3.2, but with that
I see identical result to the one I described before.
Is there issue with the Linux version?

Tomas

On Dec 17, 5:34 pm, Luis Mendoza <[email protected]> wrote:
> Hello Tomas,
> The behavior you describe is the default (or typical) for the original
> ProteinProphet tool.  As of TPP version 4.2.0. (released February 2009),
> subsumed proteins are "grouped" with their parent ones and displayed under a
> single entry.  Please upgrade your TPP to take advantage of this and other
> features, including the MININDEP option in ProteinProphet.  The release
> notes when this change was made can be found 
> here:http://groups.google.com/group/spctools-discuss/browse_thread/thread/...
>
> Hope this helps,
> --Luis
>
> On Thu, Dec 17, 2009 at 2:46 PM, Tomas <[email protected]> wrote:
> > I have a peculiar problem - two highly homologous proteins where I
> > identified bunch of peptides for one of them (including peptides
> > unique for it) and for the other I "identified" only peptides which
> > are shared by both proteins. The TPP (ProteinProphet) gives the first
> > one protein probability 1.0 and the second probability 0.0 (as
> > expected), but it separates them in the output, e.g. does not generate
> > a "protein group" where the first would be the main protein and the
> > other an "indistinguishable" group member. Instead what TPP did is
> > that it indicated the second one as a "subsumed entry" of the first
> > one as well as listing it separately as a protein with 0.0 protein
> > probability (giving it unique protein number).
> > Would anybody have explanation why not a group but subsumed entry and
> > what is the distinction between these two?
>
> > I use TPP v3.4 SQUALL rev.2, Build 200906181759.
>
> > Thanks,
>
> > Tomas
>
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