I havent seen any replies to this so I am taking a shot (even though I
am not even remotely the best qualified for the job).

Had started w/ long reply but thought the best tool for cmd automation
for me was to run Petunia then capture cmd line and use that going
forward.

Cannot comment on 1) 4) (not good) and 5) but for 2) and 3) my biggest
confusion is always keeping things straight on if one wishes to apply
cmds on the protein or peptide level.  So for me 2 (the cmds listed)
would be done w/ ProteinProphet (as opposed to xinteract).  These same
conds.can be applied at the peptide level w/ diff. cmds using
xinteract.  This is how I view the pipeline (I am sure many are more
sophistacated and knowledgeable in their approach) based on the
Petunia display and the cmd line it generates.

>From my understanding iProphet (which I really like) has additional
stat. tools and can be used to feed ProteinProphet.  PepProphet can
feed both.  All of these tools can be used to combine pep.xml files.
So for me PepPro feeds IPro which then feeds ProPro

Hope it helps and please anyone correct me where I am wrong.
DD

On Mar 4, 12:22 am, Simon Michnowicz <[email protected]>
wrote:
> Dear Group,
> I have several questions about running xinteract, and I'd be grateful
> if you could assist me.
> (1) I ran xinteract on an angio file,( with limited spectra).
> xinteract crashed at RefreshParser with a memory error.
>           failed to update simon-J1682.pepprophet.xml from temp file
> simon-J1682.pepprophet.xml.tmp.94fG9b, error 12 "Cannot allocate
> memory"). Is this a bug, and to whom do I report it?
> (2)  xinteract gives the option to call ProteinProphet. How do you
> specify the protein prophet command line options form xtineract? (e.g.
> ICAT  GLYC  XPRESS  ASAP_PROPHET  EXCLUDE_ZEROS  PROTLEN  PROTMW
> DELUDE  NOOCCAM  NOGROUPS  NORMPROTLEN  INSTANCES  GROUPWTS )
> (3) ProteinProphet can be called with several input files. If I used
> Mascot to analyse  many runs of a gel line, would I use ProteinProphet
> to combine the results, or would I use iProphet, and then feed the
> output of that to ProteinProphet?
> (4)I naively put in some extra command line options for xinteract. I
> added -TAA  when I ran peptideProphet, and it exited immediately with
> "with non-zero exit code: 11". Is this a problem?
> (5)PeptideProphet command line options -i, -f are mutually exclusive.
> is the absence of -i the same as the presence of -f?
>
> Thank you
> Simon Michnowicz

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