Hi Bjorn, I got it now. Thank you so much. Best regards! Bo 在 2014年5月2日星期五UTC+8上午1时06分08秒，Bjorn写道： > > Hi Bo, > Not sure if this is what you need, but the FDR formula at the PSM level is > eq. 14 on page 5391 of this paper: > Keller, A., Nesvizhskii, A. I., Kolker, E. Aebersold, R., 2002. Empirical > statistical model to estimate the accuracy of peptide identifications made > by MS/MS and database search. Anal. Chem. 74 (20), 5383–5392. > It's based on posterior probabilities of the PSMs. > > For proteins, the formula is the same, but here the probabilities are > those of the proteins (which are based on the modified probabilities of the > PSMs). > > Cheers, > Bjorn > > > > > > > > On Thursday, 24 April 2014 15:53:15 UTC+2, Bo wrote: >> >> Hi, >> Does anyone know TPP how to calculate the PSM-level FDR and peptide-level >> FDR? >> Many thanks and best regards! >> Bo >> >
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