There are many things that could be wrong. It would probably be most
efficient if you would make available to us some of these files, perhaps
the originals and ones that you have attempted to fix. We could probably
come up with an example of a file that can be processing by PeptideProphet
and then you could ask the M2Lite developers to fix the exported pepXML to
be complete.



Regards,

Eric





*From:* [email protected] [mailto:
[email protected]] *On Behalf Of *delphine wood
*Sent:* Wednesday, June 18, 2014 1:30 AM
*To:* [email protected]
*Subject:* Re: [spctools-discuss] peptide prophet "read in no data"



Hi David,

My aim was not to get a meaningful result but to see if peptideprophet
could work with the pepxml I'm trying.

I used the M2Lite software to transform msf files to pepxml files. The
problem is that this option is not yet completely finished and thus I'm
looking for the changes requiered so that the pepxml works with
peptideprophet. In the example I pasted in the post there were only five
peptides because I wanted to see if adding values for "deltacn",
"sscan","spscore" and "sprank" would help; with 10 peptides it still
doesn't work...

I checked the is_rejected="1" in the file created during the begining of
peptideprophet and not all the peptides were rejected...



Without the sequest variables and with many peptides I still get the same
problem of "read in no data"... Could you tell me  what can cause this
problem? I don't really know where to look now...

Thanks

Delphine



2014-06-17 18:56 GMT+02:00 David Shteynberg <
[email protected]>:

Hi Delphine,

Perhaps all of the 5 peptides in the file are not of sufficient length
and get set to is_rejected="1" in the pepXML file after
InteractParser, so PeptideProphet cannot use them.  Also 5 peptides
are much to few to get a meaningful PeptideProphet result.

-David


On Tue, Jun 17, 2014 at 3:38 AM, Delphine <[email protected]> wrote:
> Hello,
> I get this error when I'm using peptideprophet and I would like to
> understand the meaning of the "read in no data", which seems to be the
> beginning of the problem.
> Could someone help me?
> Thanks
>
> Delphine
>
> PS: TPP output:
>
>
> SUCCESS: CORRECTED data file
>
C:/Inetpub/wwwroot/ISB/data/test_mslite/TCGA_114C_59-2372-01A-01_24-1548-01A-01_29-1762-01A-01_W_JHUZ_20130903_F1.mzXML
> in msms_run_summary tag ...
>  processed altogether 5 results
> INFO: Results written to file:
> c:/Inetpub/wwwroot/ISB/data/test_mslite/interact.pep.xml
> command completed in 1.403e+009 sec
>
> running: "C:/Inetpub/tpp-bin/DatabaseParser "interact.pep.xml""
> command completed in 1.403e+009 sec
>
> running: "C:/Inetpub/tpp-bin/RefreshParser "interact.pep.xml"
> "C:/Inetpub/wwwroot/ISB/data/test_mslite/human.protein.faa""
>   - Searching the tree...
>   - Linking duplicate entries...  - Printing results...
>
>   - Building Commentz-Walter keyword tree...command completed in
1.403e+009
> sec
>
> running: "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> MINPROB=0.0"
>  (SEQUEST) (minprob 0)
> init with SEQUEST trypsin
> MS Instrument info: Manufacturer: UNKNOWN, Model: UNKNOWN, Ionization:
> UNKNOWN, Analyzer: UNKNOWN, Detector: UNKNOWN
>
>  PeptideProphet  (TPP v4.7 POLAR VORTEX rev 0, Build 201402281256 (MinGW))
> AKeller@ISB
>  read in 0 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, and 0 7+ spectra.
>  read in no data
>
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