Hi David,

We will try to compile the PTMProphet code from the svn repository: could
you tell me how to access this repository please?

Thanks.

Delphine

2015-06-05 21:48 GMT+02:00 David Shteynberg <
[email protected]>:

> Hi Delphine,
>
> Unfortunately, with the version of PTMProphet you have this will not be
> for you to process this type of data.  For linux processing, you will need
> to compile and use the latest PTMProphet code from the SVN repository, as
> it is not available as a release yet.  Alternatively, you can install the
> windows version of the code on another machine, migrate your results and
> run the binary I sent a link for that includes the latest PTMProphet code.
> Our build manager has recently switched jobs so the building of the
> software and the releases have been lagging behind the development at the
> moment.
>
> Thanks for you patience,
>
> -David
>
>
>
> On Fri, May 22, 2015 at 5:54 AM, Delphine <[email protected]> wrote:
>
>> Hello,
>>
>> I recently asked a question about mods error for the methylation
>> identifications with  PTMprophet (
>> https://mail.google.com/mail/u/0/#14d15557e5baa348_group_thread_1). You
>> helped me to partially solve the problem. Now I have to identify
>> methylation, di-methylations and tri-methylations on the same data. I
>> modified the interrogation parameter files:
>>   -comet:
>> variable_mod01 = 15.9949 M 0 3 -1 0
>> variable_mod02 = 14.015650 K 0 3 -1 0
>> variable_mod03 = 28.031300 K 0 3 -1 0
>> variable_mod04 = 42.046950 K 0 3 -1 0
>>   -xtandem:
>> <note type="input" label="residue, modification mass">57.021464@C</note>
>> <note type="input" label="residue, potential modification
>> mass">15.994915@M,14.015650@K,28.03130@K,42.046950@K</note>
>>
>>
>> I combine the identification results with iprophet (file joined)  and
>> tried to use PTMprophet on this file.
>>
>> Here is the command line:
>>
>> * cd /opt/tpp/data/327_05_01_1704_multimethylations;
>> /opt/tpp/bin/PTMProphetParser K,14.0156,K,28.03130,K,42.046950,M,15.9949
>> MZTOL=0.2
>> /opt/tpp/data/327_05_01_1704_multimethylations/327_05_01_014_150417_01_MTCS_0_D_interact.iproph.pep.xml
>> 327_05_01_014_150417_01_MTCS_0_D_interact.ptm.pep.xml *
>> Here is the error:
>>
>>
>> INFO: Writing file 327_05_01_014_150417_01_MTCS_0_D_interact.ptm.pep.xml ...
>> INFO: Reading file 
>> /opt/tpp/data/327_05_01_1704_multimethylations/327_05_01_014_150417_01_MTCS_0_D_interact.iproph.pep.xml
>>  ...WARNING: Illegal peptide with unknown mod: DGDPLEK[156]WARNING: Illegal 
>> peptide with unknown mod: NLM[147]TGMKWARNING: Illegal peptide with unknown 
>> mod: NLMTGM[147]KWARNING: Illegal peptide with unknown mod: 
>> K[156]AGESHRWARNING: Illegal peptide with unknown mod: IITNLSK[156]WARNING: 
>> Illegal peptide with unknown mod: AM[147]NVNPK[156]WARNING: Illegal peptide 
>> with unknown mod: C[160]PGELPRWARNING: Illegal peptide with unknown mod: 
>> LTPSM[147]LRWARNING: Illegal peptide with unknown mod: VTAAMGK[156]KWARNING: 
>> Illegal peptide with unknown mod: VTAAMGKK[156]WARNING: Illegal peptide with 
>> unknown mod: M[147]ANEVIK[142]WARNING: Illegal peptide with unknown mod: 
>> M[147]ALTQVRWARNING: Illegal peptide with unknown mod: 
>> M[147]ADAK[156]QKWARNING: Illegal peptide with unknown mod: 
>> M[147]ADAKQK[156]WARNING: Illegal peptide with unknown mod: 
>> AM[147]EAELK[156]WARNING: Illegal peptide with unknown mod: 
>> K[142]ANSMVKWARNING: Illegal peptide with unknown mod: 
>> K[142]ANSM[147]VK[156]WARNING: Illegal peptide with unknown mod: 
>> K[156]ANSM[147]VK[142]WARNING: Illegal peptide with unknown mod: 
>> KANSMVK[142]WARNING: Illegal peptide with unknown mod: K[142]VPSAPPKWARNING: 
>> Illegal peptide with unknown mod: KVPSAPPK[142]WARNING: Illegal peptide with 
>> unknown mod: AEHSELK[156]WARNING: Illegal peptide with unknown mod: 
>> AEHSELK[156]WARNING: Illegal peptide with unknown mod: VASPK[156]ANKWARNING: 
>> Illegal peptide with unknown mod: VASPKANK[156]WARNING: Illegal peptide with 
>> unknown mod: AVDQRNK[142]WARNING: Illegal peptide with unknown mod: 
>> LATWK[156]PLWARNING: Illegal peptide with unknown mod: AMAEWVK[156]WARNING: 
>> Illegal peptide with unknown mod: DSFDIIK[156]WARNING: Illegal peptide with 
>> unknown mod: VPPHM[147]LRWARNING: Illegal peptide with unknown mod: 
>> LPKAEDRWARNING: Illegal peptide with unknown mod: LKDSLPRWARNING: Illegal 
>> peptide with unknown mod: KEVPLSRWARNING: Illegal peptide with unknown mod: 
>> AM[147]LAM[147]FK[156]WARNING: Illegal peptide with unknown mod: 
>> QAVGPEDK[156]WARNING: Illegal peptide with unknown mod: AM[147]LEVHK[156]
>>      WARNING: Unrecognized mod on peptide: DILTQLK[170]WARNING: Cannot 
>> initialize for sequence: DILTQLK[170], unknown mods may exist in spectrum 
>> 327_05_01_014_150417_01.15465.15465.2WARNING: Illegal peptide with unknown 
>> mod: SSVC[160]IC[160]K[156]
>> Segmentation fault
>>
>> *Command FAILED*
>>
>> RETURN CODE:35584
>>
>>
>>
>> Do you have any idea to solve this problem? What I am doing wrong?
>>
>> Thanks for your help
>>
>> Delphine
>>
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