Hi,
I am running comet database search for my 15 fraction of mzXML data file 
from WATERS QTOP.  Out of 15 fractions only 5  fractions command are 
success, remaining fraction has the following error

*EXECUTING: cd c:/Inetpub/wwwroot/ISB/data& c:\Inetpub\tpp-bin\comet 
-Pc:/Inetpub/wwwroot/ISB/data/parameters/comet.params 
-Nc:/Inetpub/wwwroot/ISB/data/parameters/17052016_NISHAD_ITRAQ_1 
-Dc:/Inetpub/wwwroot/ISB/data/parameters/Chicken.fa 
17052016_NISHAD_ITRAQ_1.mzXML *

 Warning - invalid parameter found: precursor_tolerance_type.  Parameter will 
be ignored.
 Warning - invalid parameter found: require_variable_mod.  Parameter will be 
ignored.
 Warning - invalid parameter found: mass_offsets.  Parameter will be ignored.
 Warning - invalid parameter found: add_U_selenocysteine.  Parameter will be 
ignored.
 Comet version "2014.02 rev. 2"

 Search start:  06/12/2016, 11:21:12 PM
 - Input file: 17052016_NISHAD_ITRAQ_1.mzXML
 - Load and process input spectra

*Command FAILED*
RETURN CODE:65280

Kindly help some one what could be the reason?how can i solve this problem?

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