Hi Everyone,

I am analyzing peptides from cells that have been treated with a UV 
crosslinker attached to a small molecule (ABPP method). This results in 
mono-linked peptides. Because the UV cross-linker is not residue specific, 
I am forced to search the data in comet with a modification of 639.3118 Da 
on any amino acid other than those with fixed modifications. I am able to 
process the output files until the iProphet step, but am running into 
command failure at PTM Prophet. Is there a maximum limit on the number of 
amino acids used at once in a single line entry for a modification? I have 
attached screenshots of the parameters used and the command failure output.

Thanks!


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