Dear Matthew, did you find a solution for this? I have the exact same 
question as I also try use a recently generated skyline library in 
spectraST. 
Matthew Russell schrieb am Dienstag, 26. Januar 2021 um 06:22:08 UTC+1:

>
> Hi
>
> I am trying to put together a processing pipeline from Waters MSe data to 
> spectrast. I can process data with Waters own tools to generate a spectral 
> library, and then use skyline and blib to convert to .ms2 format. I would 
> like to put that as an input to spectrast to make a .sptxt / .splib file. 
> However, when I do that the retention time information is not carried 
> through to .sptxt file.
>
> Is there a way to propagate retention time into the spectrast data files? 
> I wondered if the retention time is not labelled the way spectrast expects 
> in my .ms2 file. In which case I could fix it with a program like sed. 
> Alternatively I wondered if I used the wrong switch. Any help would be very 
> welcome.
>
> The command line I used was essentially: 
>
> spectrast.exe -V -cNmyBaseName mySpectra.ms2
>
> The first spectra in my .ms2 and .sptxt files is below showing the 
> presence and then absence of the retention time information.
>
> ######
> .ms2:
>
> H CreationDate Mon Jan 18 22:01:43 2021
> H Extractor BlibToMs2
> H Comment Library 
> D:/Repositories\p20_05_HaloSpecLibPaper_SciData\splib\halo.blib
> S 1 1 1278.65
> *I RTime 84.7206*
> Z 2 2481.75
> D seq AAAANPGSAKAIADLGGAEGALTQAMGR
> D modified seq AAAANPGSAKAIADLGGAEGALTQAM[+15.99492]GR
> 693.35 39.0
> 822.42 85.0
> 1006.53 48.0
> 1209.62 100.0
> 679.31 36.0
> 792.40 52.0
> 863.41 67.0
> 1049.49 76.0
> 1031.49 66.0
> 1120.54 67.0
> 1103.50 67.0
> 1330.66 84.0
>
> ####
> .sptxt:
>
> Name: AAAANPGSAKAIADLGGAEGALTQAM[147]GR/2
> LibID: 0
> MW: 2557.2908
> PrecursorMZ: 1278.6454
> Status: Normal
> FullName: K.AAAANPGSAKAIADLGGAEGALTQAM[147]GR.L/2 (CID-QTOF)
> Comment: AvePrecursorMz=1279.4240 BinaryFileOffset=308 
> FracUnassigned=0.00,0/5;0.00,0/20;0.00,0/12 
> Fullname=X.AAAANPGSAKAIADLGGAEGALTQAM[147]GR.X/2 Mods=1/25,M,Oxidation 
> NAA=28 NMC=1 NTT=2 Pep=Tryptic PepContext=1/AGLK_LNVV Prob=1.0000 
> Protein=1/fig|2745.389.peg.2815 ScanNum=1.1 Spec=CREATE
> NumPeaks: 12
> 679.3100 3600.0 y6/-0.009 
> 693.3500 3900.0 b9-18/0.019,b9-17/-0.965 
> 792.4000 5200.0 y7/-0.003,y17-64^2/0.487 
> 822.4200 8500.0 b10-17/0.010,b10-18/0.994 
> 863.4100 6700.0 y8/-0.030 
> 1006.5300 4800.0 b12-17/-0.002,b12-18/0.982 
> 1031.4900 6600.0 
> y10-18/-0.004,y10-17/-0.988,y22^2/0.467,b24-44^2/-0.558,b24-45^2/-0.042,b24-46^2/0.450
>  
>
> 1049.4900 7600.0 y10/-0.014,b13-45/-0.084 
> 1103.5000 6700.0 y11-17/-0.015,y11-18/0.969 
> 1120.5400 6700.0 y11/-0.002,y24-35^2/1.487 
> 1209.6200 10000.0 b14/-0.002 
> 1330.6600 8400.0 y14-17/0.018
>

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