Thanks Luis. I have asked this on the COMET group as well. They will 
probably come up with an update or something to enable it.
On Tuesday, August 1, 2023 at 8:47:46 AM UTC+5:30 Luis Mendoza wrote:

> Hi Debojyoti,
> Yes, I would say this is the most straightforward way of conducting this 
> search.
> Note that you may need to make further adjustments to the variable mod 
> string settings if, say, a given peptide must have *all* of its Cysteines 
> in one state (+50) or the other (+90).  The default is to allow for mixed 
> Cysteines in the peptide, e.g. PEPC[50]TIDEC[90]R.
> Hope this helps,
> --Luis
>
>
> On Mon, Jul 31, 2023 at 11:04 AM Debojyoti Pal <[email protected]> 
> wrote:
>
>> Hello everyone
>>
>> I have a specific scenario where I want to search for peptide in which 
>> cysteine must either have +50 or +90 mod. Basically:
>> 1) Cys can only have one of +50 or +90
>> 2) Cys much have one of +50 or +90 (ie It cannot be unmodified)
>>
>> Only way I can achieve this is to put a static mod of +50 and variable 
>> mod of +40 (40+50 = +90). Is there any better way to do this.
>>
>> Regards
>> Debojyoti
>>
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