I've actually got two questions on different subjects, so I'll send them
separately if that's ok?
The first is about the B12 co-enzyme cobamamide/dibencozide.  I've been
studying the ISSA's specialist in Performance nutrition course (SPN) & I
stumbled across a throw-away remark.  I'm sure you lot are like me & hate
unreferenced statements (especially in things like nutritional educational
work!), but it was basically claiming that B12 co-enzyme was compared to
(unspecified type or amount of) anabolic steroids in a head to head study &
was given to children with growth disorders.  The results were that the B12
gave a greater growth response than the anabolic steroids?
Now, as far as I know, cobamamide/dibencozide isn't a banned substance
(which it would be if it had an anabolic effect I'd have thought).  I would
think it might increase appetite some (as I know that can be an effect of
increased B12 intake).
But, first off has anyone heard of any studies done upon this type of B12
(any links to research etc would be great), also it does sound another of
those very dubious claims you find in the muscle comics (as I like to call
them).
Anyway, if anyone has any information or thoughts, then that would be great.

By the way I would not take too much notice of claims like this, but it's
in part of my course material & I don't want to be absorbing inaccurate
information...Oh yes, & I do realise that even if the effect was seen on
children with growth defects, it might well not have the same effect on
healthy adults.

I scouted around pubmed, but could only find these.  Maybe someone has
access to these journals?
As a final note I was talking to an older bodybuilder I know & they said
they think they remembered this supplement being around in the late
70's/early 80's, so it could well be just "making a comeback", so to speak.

Pete
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Ab
stractPlus&list_uids=4105627&query_hl=4&itool=pubmed_docsum

1: Minerva Pediatr. 1971 May 19;23(30):914-21. Links 
[Enhancement of steroid anabolism by the association of cobamamide]
[Article in Italian]
Olivi O, 
Mugnaini P, 
Di Battista C. 
PMID: 4105627 [PubMed - indexed for MEDLINE]

Related Links
[Clinico-experimental results of the simultaneous administration of an
anabolic steroid and vitamin B 12 coenzyme in a group of subjects in the
second and third ages of childhood] [Minerva Pediatr. 1971] PMID: 5131917 
[Evaluation of parenterally and intragastrically administered amino acid
solutions] [Wien Med Wochenschr. 1971] PMID: 5560228 
[Controlled studies of the comparative effects of an anabolic steroid
(quinbolone) and cobamamide on weight gain, skinfold thickness and secondary
sex characters in a group of children of both sexes. Preliminary note]
[Minerva Pediatr. 1972] PMID: 5073979 
[Study of the relationship of protein fractions in the serum of microbe-free
guinea pigs using the method of disk electrophoresis] [Biull Eksp Biol Med.
1969] PMID: 4097860 
Age-related trends of the amylase, glycoprotein, lipoprotein and serum
protein in human blood. [Exp Gerontol. 1968] PMID: 5719622 
See all Related Articles... 
 
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Ab
stractPlus&list_uids=5073979&query_hl=4&itool=pubmed_docsum

1: Minerva Pediatr. 1972 Jul 14;24(25):1040-50. Links 
[Controlled studies of the comparative effects of an anabolic steroid
(quinbolone) and cobamamide on weight gain, skinfold thickness and secondary
sex characters in a group of children of both sexes. Preliminary note]
[Article in Italian]
Riscaldini F, 
Bruni G, 
Mariottini F, 
Rezza E. 
PMID: 5073979 [PubMed - indexed for MEDLINE]

Related Links
[Clinico-experimental results of the simultaneous administration of an
anabolic steroid and vitamin B 12 coenzyme in a group of subjects in the
second and third ages of childhood] [Minerva Pediatr. 1971] PMID: 5131917 
[Enhancement of steroid anabolism by the association of cobamamide] [Minerva
Pediatr. 1971] PMID: 4105627 
[Human pharmacological study of quinbolone. Clinical and laboratory
investigations of the effects of anabolic treatment in aged women] [G
Gerontol. 1972] PMID: 5042390 
[New combination of amino acids and cobamamide. Therapeutic use in premature
infants] [Minerva Pediatr. 1972] PMID: 5037198 
[Pituitary function during treatment with quinbolone] [G Gerontol. 1971]
PMID: 5143556 
See all Related Articles...






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