Hey,
thank you very much for your reply.

- WIndows 7 (i7-4702MQ, 8GB Ram)
- Python(x,y) Version 2.7.10
- numpy 1.9.2-8
-scipy: 0.15.1-8
-spyder 2.3.5.2-17

Script:
import numpy as np
import scipy.io as sio
# MatlabStruct.mat is a struct with 4 fields (each 250.000 double values)
Result= sio.loadmat(r"...MatlabStruct.mat")
# import data from field name data1
data1 = daten[0,0]['data1']

...if data1 is in the variable explorer - spyder is extremely slow. 

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