This might be a wild goose chase, and I'm not convinced it's directly related, but AMD multi-core CPUs are known to have timing issues. Google for "AMD negative ping" and you'll see it affects the results from the ping utility for example. They've released a "Dual-Core Optimizer" patch to correct this: http://www.amd.com/us-en/Processors/TechnicalResources/0,,30_182_871_13118,0 0.html
This is backwards from your situation, but it at least demonstrates issues in a related area, so perhaps there's something there. Doug > -----Original Message----- > From: [EMAIL PROTECTED] [mailto:sqlite-users- > [EMAIL PROTECTED] On Behalf Of Benilton Carvalho > Sent: Monday, September 08, 2008 2:20 PM > To: [email protected] > Subject: [sqlite] SQLite vs. quad-cores > > Hi everyone, > > I'm a BioConductor developer and we use SQLite (via RSQLite package) to > handle annotation of high-density oligonucleotide microarrays. > > Our solution, implemented in the pdInfoBuilder package, worked great > until > we got machines with quad-core processors. One particular setup is a > machine > with 2 Quad-Core AMD Opteron Processor 2356. The processes that usually > took > 1-2 hours on older machines (dual-cores AMD), now take 6-8 hours on the > new > computers. > > We thought there would be something wrong with our switch (given the > particular network scenario we have here), and changing it didn't solve > the > problem. Later, we decided to run everything on local storage (instead > of > network), and the same behavior was observed again. > > Is there anything else that you guys could recommend? > > thanks a bunch, > > benilton > _______________________________________________ > sqlite-users mailing list > [email protected] > http://sqlite.org:8080/cgi-bin/mailman/listinfo/sqlite-users _______________________________________________ sqlite-users mailing list [email protected] http://sqlite.org:8080/cgi-bin/mailman/listinfo/sqlite-users

