> >httpd_accel_host virtual

I do not think you really intend the above.. you should most likely use 
the main domain name there. Not very important however.

> >httpd_accel_single_host off
> >httpd_accel_uses_host_header on
> >httpd_accel_with_proxy  on
> >httpd_accel_port 80
> > 
> >visible_hostname  centralmail
> >acl all src 0.0.0.0/0.0.0.0
> >http_access allow all

The above you certainly do not want. Makes your "reverse proxy" a open 
proxy allowing anyone to connect via the proxy to anywhere in the world on 
any service doing anything they like.

> >     The problem is when I access the webmail from both DMZ and
> >Internet, the web page returns an error message about access denied.
> >What 's wrong? 

I do not see how you can get an access denied with the above totally wide 
open setup.

What does access.log say?

Any output from "squid -k parse"?

Regards
Henrik

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