I believe the reason you are not getting a solution (originally) is related 
to https://github.com/sympy/sympy/issues/8789 .

On Friday, January 16, 2015 at 1:20:49 PM UTC-6, Junwei Huang wrote:
>
> Thanks very much, Chris. That solves the problem. 
>
> On Fri, Jan 16, 2015 at 2:09 PM, Chris Smith <[email protected] 
> <javascript:>> wrote:
>
>> (actually, you don't need to factor, but doing so shows the quadratic 
>> nature of the thing). I get for approx. solutions, +/- 2.6.
>>
>> On Friday, January 16, 2015 at 1:06:18 PM UTC-6, Chris Smith wrote:
>>>
>>> The expression is quadratic in C0 only if C0 is positive. Try replace C0 
>>> with var('x', positive=True); factor the result, *then* solve for your two 
>>> values.
>>>
>>> On Wednesday, January 14, 2015 at 4:44:28 PM UTC-6, Junwei Huang wrote:
>>>>
>>>> Hi all, I have a symbolic expression as in polyC
>>>>
>>>> In [46]: polyC
>>>> Out[46]: -(sqrt(2035953389603699)*sqrt(-1/C0**12)/2000000 - 
>>>> 4849598923/(54000000*C0**6))**(1/3) - 1 + 3599/(300*C0**2) - 
>>>> 368417/(18000*C0**4*(sqrt(2035953389603699)*sqrt(-1/C0**12)/2000000 - 
>>>> 4849598923/(54000000*C0**6))**(1/3))
>>>>
>>>> In [47]: N(polyC,2)
>>>> Out[47]: -(23.0*(-1/C0**12)**0.5 - 90.0/C0**6)**0.33 - 1.0 + 12.0/C0**2 
>>>> - 20.0*(23.0*(-1/C0**12)**0.5 - 90.0/C0**6)**(-0.33)/C0**4
>>>>
>>>> In [48]: polyC.simplify()
>>>> Out[48]: -1 - (54*sqrt(2035953389603699)*sqrt(-1/C0**12) - 
>>>> 9699197846/C0**6)**(2/3)/(600*(27*sqrt(2035953389603699)*sqrt(-1/C0**12) 
>>>> - 4849598923/C0**6)**(1/3)) + 3599/(300*C0**2) - 
>>>> 368417*2**(1/3)/(60*C0**4*(27*sqrt(2035953389603699)*sqrt(-1/C0**12) - 
>>>> 4849598923/C0**6)**(1/3))
>>>>
>>>> In [49]: solve(polyC.simplify(),C0)
>>>> Out[49]: []
>>>>
>>>> In [50]: solve_poly_system([polyC.simplify()],C0)
>>>> PolynomialError: C0**(-2) contains an element of the generators set
>>>>
>>>>
>>>> But if you exam Out[46], polyC seems to be something like 
>>>> C0**2*(expr)-1. then C0 can be solved with two roots. Anything I missed? 
>>>> Thank you.
>>>>
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