It looks like pympler works pretty well on sympy symbols, here is my 
notebook:

https://gist.github.com/denfromufa/4d0e6a94f70fac155b66


On Monday, August 24, 2015 at 10:03:30 PM UTC-5, Denis Akhiyarov wrote:
>
> Nbytes is very hard in Python, and getsizeof() does not work very well. 
> People has addressed this using github.com/pympler.
> Not sure if anyone tried it on sympy objects and how costly is that 
> calculation. Cachey has very simple nbytes calculation, mainly intended for 
> numpy and pandas objects.
>

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