I installed it on amd64/current(kvm guest), it work. Host: debian/amd64 Guest: openbsd/amd64
(add 3 lines to /usr/src/sys/arch/amd64/conf/GENERIC for enable amd64) +virtio* at pci? # Virtio PCI device +vioblk* at virtio? # Virtio block device +vioif* at virtio? # Virtio network device I tested on bsd.sp and bsd.mp, both work. I running it a week(few hours per day). I running chrome, pf and building the kernel without a problem I feeling bsd.mp is more fast to run chrome and xfce4. vioif0: flags=8843<UP,BROADCAST,RUNNING,SIMPLEX,MULTICAST> mtu 1500 lladdr 00:aa:bb:cc:dd:07 priority: 0 groups: egress media: Ethernet autoselect status: active inet6 fe80::2aa:bbff:fecc:dd07%vioif0 prefixlen 64 scopeid 0x1 inet 192.168.168.107 netmask 0xffffff00 broadcast 192.168.168.255