For the biologists:  
<http://www.laboratoryequipment.com/news-microbes-more-diverse-than-thought.aspx>

Mark Minton

Extreme Microbes More Diverse Than Thought
May 28, 2009
Researchers at the Univ. of Illinois report that microbes able to live in 
boiling acid are more diverse than previously thought, and that their diversity 
is driven largely by geographic isolation. Sulfolobus islandicus is offering up 
its secrets to researchers hardy enough to capture it from the volcanic hot 
springs where it thrives.
The findings open a new window on microbial evolution, demonstrating for the 
first time that geography can trump other factors that influence the makeup of 
genes an organism hosts. S. islandicus belongs to the archaea, a group of 
single-celled organisms that live in a variety of habitats including some of 
the most forbidding environments on the planet. Once lumped together with 
bacteria, archaea are now classified as a separate domain of life.
"Archaea are really different from bacteria - as different from bacteria as we 
are," said Rachel Whitaker, a professor of microbiology. Whitaker has spent 
almost a decade studying the genetic characteristics of S. islandicus. The 
extreme physical needs of S. islandicus make it an ideal organism for studying 
the impact of geographic isolation. It can live only at temperatures that 
approach the boiling point of water and in an environment that has the pH of 
battery acid. It breathes oxygen, eats volcanic gases and expels sulfuric acid. 
It is unlikely that it can survive even a short distance from the hot springs 
where it is found.
By comparing the genetic characteristics of individuals from Yellowstone 
National Park, Lassen Park, and a Russian volcano, Whitaker was able to see how 
each of the populations had evolved since they were isolated from one another 
more than 900,000 years ago.
The complete genome of S. islandicus contains a set of core genes that are 
shared among all members of this group, with some minor differences in the 
sequence of nucleotides that spell out individual genes. But it also contains a 
variable genome, with groups of genes that differ - sometimes dramatically - 
from one subset, or strain, to another.
Whitaker found that the variable genome in individual strains of S. islandicus 
is evolving at a rapid rate, with high levels of variation even between two or 
three individuals in the same location.
"Some people think that these variable genes are the way that microbes are 
adapting to new environments," Whitaker said. "You land in a new place, you 
need a new function in that new place, you pick up that set of genes from 
whoever's there or we don't know who from, and now you can survive there. We've 
shown that does not occur."
"This tells you that there's a lot more diversity than we thought," Whitaker 
said. "Each hot spring region has its own genome and its own genome components 
and is evolving in its own unique way. And if each place is evolving in its own 
unique way, then each one is different and there's this amazing diversity. I 
mean, beetles are nothing compared to the diversity of microbes."
These findings challenge the idea that microbes draw whatever they may need 
from a near-universal pool of available genetic material, Whitaker said. It 
appears instead that S. islandicus, at least, acquires new genes from a very 
limited genetic reservoir stored in viruses and other genetic elements that are 
constrained to each geographic location on Earth.
Source: Univ. of Illinois
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