Pranam

Cancer, one of the most deadly challenges spreading drastically in
21st century,
has now officially become the most dangerous killer in the world according
to the World Health Organization. Who can deny the fact that cancer is
related to the adversary of modernization and an advanced pattern of
irregular and stressed life dominated by Western medicine. Scientists are
making their best efforts to fight this disease; however the sure-shot cure
is still awaited.  Ayurveda, the oldest Indian indigenous medicine system
of plant drugs is known from very early times for preventing or suppressing
various tumours using these natural drugs. And nowadays scientists are
keener to research on complementary and alternative medicine for the
management of cancer. In Ayurvedic concept, according to ‘Charaka’ and
‘Sushruta Samhitas’ cancer is described as inflammatory or non-inflammatory
swelling and mentioned either as ‘Granthi’ (minor neoplasm) or ‘Arbuda‘
(major neoplasm).  The nervous system (Vata or air), the venous system
(Pitta or fire) and the arterial system (Kapha or water) are three basics
of Ayurveda and very important for normal body function. In malignant
tumours all three systems get out of control (Tridoshas) and lose mutual
coordination that causes tissue damage, resulting in critical conditions.
Tridoshas cause excessive metabolic crisis resulting in proliferation  (B P
Govindarajan on sushruta samhita). Although our understanding of signalling
pathways and transcription factors in chronic inflammation primarily comes
from pre-clinical studies, these data have clinical relevance since certain
anti-inflammatory drugs (such as nonsteroidal anti-inflammatory drugs
(NSAIDs) and COX-2 specific inhibitors) have proven anti cancer effects in
preclinical tumour models and clinical trials. These anti-inflammatory
drugs interfere with eicosanoid signalling and metabolism, suppress the
neoplastic process, and can decrease oxidative stress and angiogenesis [11].
Interestingly, the potent antitumor effects of phytochemicals, such as
curcumin, from turmeric, the green tea polyphenol epigallocatechin gallate
(EGCG), and resveratrol from grapes, are in large part attributed to their
anti-inflammatory activities . Guggulsterone, the major active component of
the gum resin from *Commiphora wightii* (or *Commiphora mukul*), is used to
treat internal tumours, obesity, liver disorders, and malignant sores and
ulcers in *Ayurveda*. Notably, guggulsterone was shown to induce apoptotic
cell death and suppress proliferation, invasion, angiogenesis and
metastasis of tumour cells . Interestingly, all four phytochemicals
(curcumin, EGCG, resveratrol, and guggulsterone) inhibit inflammation by
suppressing the transcriptional activity .In ayurveda, one’s basic “body
constitution” is termed as “*Prakriti*.” *Prakriti* arises due to a unique
combination of fixed amounts of the three *Doshas* at the time of
conception. Thus, *Prakriti* determines individuality and is akin to one’s
genotype. *Ayurveda* recognizes seven main types of *Prakritis*, based on
the different combinations of the three *Doshas* at conception.
Experimental analysis of the *Prakriti* concept revealed statistically
significant correlations between an individual’s *Prakriti* and the
expression of specific genes and biochemical parameters . Another study
found correlations between *Prakriti* and HLA gene polymorphisms . Although
one’s *Prakriti *(genotype) is fixed, one’s *Doshas* are in dynamic
equilibrium, and optimal function of each *Dosha* and normal interactions
between *Doshas* are essential for good health. Accordingly, individuals
with “balanced” *Doshas *(*Sama Prakriti*) are less susceptible to disease
than individuals with abnormal *Doshas*. In fact, imbalances or disturbed
interactions between *Doshas* are considered a major cause of disease. An
abnormal *Dosha* can be inhibited, excessive, or vitiated (disturbed)  Indeed,
the type and nature of disease are primarily determined by the *Dosha* which
is affected. For example, inflammatory diseases are associated with
vitiation of *Pitta Dosha*, whereas obesity and metabolic syndrome are
associated with vitiation of *Kapha Dosha *[45, 46]. A specific illness
manifests when the vitiated *Dosha(s)* interact with weaknesses in specific
organs (*Dhatus*). Conversely, pathogenic factors can also trigger
abnormality of the *Doshas* and weaken the *Dhatus* . Severe diseases, such
as cancer, affect the entire body and usually involve vitiation of all
three *Doshas*.  OBESITY IS THE MAJOR CAUSE OF THE CANCER AND THAT WAS WHY
USA WAS MUCH AFFECTED BY THE CANCER.  KR IRS 5122

On Wed, 5 Jan 2022 at 08:35, Markendeya Yeddanapudi <
[email protected]> wrote:

> How many new cancer patients are created and how many are dying every
> minute in the world today thanks to pesticides and the total pollution and
> poisoning caused by industries,agriculture,urbanization,living styles based
> on AC rooms from where hot air blows out to pollute the outside,compared to
> the hysteria created by the omicron scare.
> Why is this cancer scourge played down?Is it because of the stranglehold
> of petroleum as the foundation of economies?Is not saving nature urgent?
> YM
>
> --
> *Mar*
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  • Contrast and Paradox Markendeya Yeddanapudi
    • Re: [iyer123] Contrast and Paradox Rajaram Krishnamurthy

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