Keep Mosquitoes Away with These Tried-and-True Repellents June 2024

Mosquito experts break down how to choose and use the best mosquito
repellents

Only insect repellents with Environmental Protection Agency–registered
active ingredients such as diethyl toluamide (DEET)[AS1] ,
p-Menthane-3,8-diol (PMD) or icaridin (also known as picaridin) have been
scientifically proved to effectively keep mosquitoes away.

Mosquitoes are masters of speed and subtlety. Rarely do we catch one on our
skin mid-bite. And when we do, the damage is often already done: the blood
has been sucked, the itch-inducing saliva has been secreted, and, in some
cases, a disease has already been transmitted.

This elusiveness means we have to rely on insect repellents for the best
chance of evading bites. Not all mosquito-deterring products are created
equal, though, says Dina Fonseca, a molecular ecologist and chair of the
department of ecology at Rutgers University. Store shelves may be lined
with a plethora of sprays and gadgets such as bracelets, candles and bug
zappers purported to ward off the insects, but Fonseca and other experts
say only those with a few key active ingredients are effective. And as
greenhouse gas emissions drive up global temperatures and make already
mosquito-prone habitats even buggier, repellents may become increasingly
essential.

Scientific American spoke with experts in mosquito behaviour and avoidance
about which products are worth the purchase and how they protect us from
the pests.

What essential active ingredients should people look for in bug sprays?

Despite the vast number of brands and concoctions on the market in the
U.S., only those containing Environmental Protection Agency–registered
active ingredients such as diethyl toluamide (DEET), p-Menthane-3,8-diol
(PMD) or icaridin (also known as picaridin) have been scientifically proved
effective. Spray based on DEET, however, have long been considered supreme,
Fonseca says. “It is the oldest tried-and-true gold standard among all of
the repellents,” she says. “Back when I was a graduate student doing field
work in a mosquito-filled bog, DEET was my best friend.”

The U.S. Department of Agriculture developed this synthetic chemical in
1946 for Army personnel deployed to mosquito-infested environments. At that
time, it was used in a spray—nicknamed “bug juice”—that was 75 percent DEET
and 25 percent ethanol. Bug juice irritated skin with scratches or cuts,
and it held mosquitoes off for only a couple of hours. But later, the USDA
and Army produced a new, longer-lasting and gentler formula called extended
duration topical insect/arthropod repellent (EDTIAR), which had no ethanol
and contained just 33 percent DEET. It also included polymers that
thickened the spray to help slow its evaporation—and it remains the go-to
repellent for today’s military.

U.S. authorities approved DEET-based products, with various concentrations
of the chemical, for the general public in 1957. Currently about 120
EPA-endorsed DEET mixtures, made by about 30 companies, are sold and
considered safe for people of all ages, according to EPA evaluations
(though users should avoid getting these products in their eyes or mouth).
DEET-based repellants are a popular choice for people who spend extended
periods in outdoor places with mosquitoes and other biting insects.

PMD is a strong DEET alternative, Fonseca says, especially for people who
are seeking a naturally occurring chemical or put off by DEET’s strong odor
and greasy texture. PMD is found in eucalyptus plants and, combined with
water and a small amount of ethanol, is sometimes sold under the name “oil
of lemon eucalyptus.” Icaridin is another synthetic option, Fonseca adds,
noting that the latter is often sold in lower concentrations than DEET and
PMD and therefore must be applied more often.

How do DEET and other chemicals repel mosquitoes?

How exactly DEET works is still a subject of debate, says Aaron Gross, a
toxicologist at Virginia Tech’s Molecular Physiology & Toxicology
Laboratory. Some studies suggest that DEET targets specific receptors in
mosquitoes’ antennae and blocks their ability to smell chemicals in exhaled
breath and on skin that attract them to humans. Other research proposes
that the chemical toys with mosquitoes’ brain by manipulating their
neuronal receptors. “Everyone seems to have a different opinion,” Gross
says. “We really don’t have a clear, concise way of knowing how DEET exerts
its repellent.... All we know is that it effectively disrupts the
mosquitoes’ host-seeking behavior.”

“It is the oldest tried-and-true gold standard among all of the repellents.
Back when I was a graduate student doing field work in a mosquito-filled
bog, DEET was my best friend.”

PMD and icaridin are no less mysterious. Many experts believe that, like
DEET, these products somehow hinder mosquitoes’ senses and thus their
ability to hunt down blood meals. But the exact mechanisms are still
unknown—and Gross notes that testing such insect repellents’ efficacy isn’t
particularly easy or enjoyable: most trials require a human subject to
stick a repellent-treated forearm into a mosquito-filled cage. “I work with
a friend who once needed to test a repellent,” Fonseca says. “He coated the
front and back of my hand with the spray and I put my hand inside the cage
of mosquitoes. It was too late before I realized that we hadn’t sprayed the
stuff between my fingers, and when I took out my hand, I saw that I’d been
bitten on the inside of every single one of them.” This, she adds,
clarifies the importance of ensuring every bit of exposed skin is coated if
one is relying on a bug spray. How often a repellent should be reapplied
depends on the concentration of the product’s active ingredient; sprays
with a higher percentage of that chemical work longer, but they may be
smellier and stickier. “It’s always best to just follow the label because
all of the formulas can be a little different,” Fonseca says.

What about other mosquito-repelling products that aren’t applied on skin?

Clothing treated with the insecticide permethrin is very safe and
effective, says Eric Day, an entomologist and manager of Virginia Tech’s
Insect Identification Laboratory. Rather than actively repelling
mosquitoes, permethrin—a synthetic version of a chemical that occurs
naturally in chrysanthemum flowers—paralyzes and kills insects by
overstimulating their nervous system. As a repellent, it’s too harsh to be
applied directly to skin, but permethrin doesn’t cause irritation when
small amounts are infused in clothes. It’s still necessary, though, for
people to apply bug spray to any bit of skin that is not covered by the
treated clothing.

There are also some candles that are made with citronella oil, which is
found in some species of lemongrass, that can help ward off mosquitoes and
other pests when burned. But insects tend to avoid smoke in general,
Fonseca says, so it’s difficult to say if citronella is what really does
the trick.

Day says that most other products such as bracelets, bug zappers and
high-frequency sonic devices haven’t been scientifically validated and
typically aren’t worth buying. “Whenever I look in a bug zapper there are
very few mosquitoes and usually just other bugs from the environment,” he
says. “A lot of these products market themselves as ‘natural’ alternatives
to things like DEET, but they don’t actually do much.” Some marketers also
claim that certain plants with specific chemicals and strong fragrances can
deter mosquitoes, but there is scant scientific basis for this.

How can people prevent mosquitoes around their homes?

Female mosquitoes lay their eggs in stagnant water, and Day says cleaning
out gutters and emptying rain buckets or planter pots is a good way to keep
the insects at bay—especially in areas where mosquito-carried diseases and
pathogens such as malaria, West Nile virus and Zika virus are prevalent. If
mosquito larvae are spotted in still water, some research suggests that
adding a few drops of boric acid to the water can poison the larvae and
prevent them from hatching.

As climate change progresses and global temperatures rise, it’s likely that
some warm and wet environments will see growing mosquito populations and
more disease outbreaks. Having a strong insect repellent on hand is
becoming increasingly important, Fonseca says, and she encourages people
living in mosquito-infested places to start considering it a part of their
regular skin-care habits. “I think that one of the biggest problems is that
we really haven’t been that good at diligently using repellents,” she says.
“We’re starting to get better at this with sun protection by putting on SPF
products every morning with our face lotions and creams. But I think it’s
time that many of us, especially those really sensitive to mosquito bites,
start incorporating repellents into our daily routines.”

K Rajaram IRS 25624

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