Check Startech (https://www.startech.com). They have a range of RS-232 and similar I/O cards and at least the last time I bought one several years ago, the chip emulated a 16550 UART and didn't seem to have more jitter than any other serial board I'd tried.

John
----

On 11/6/21 12:32 PM, Chris Caudle wrote:
    On Nov 5, 2021 9:14 PM, Rich Wales <[email protected]> wrote:

      > If we could find PCI or PCIe serial cards

    The old Exar product line that MaxLinear acquired might still have PCIe
    UART.
    https://www.maxlinear.com/product/interface/uarts/pcie-uarts/xr17v352
    If you could find those on a card they should be good performance.  I
    haven't measured the performance of the UARTs in super IO chips.  Those
    would share the upstream connection with a lot of other things, so
    might vary in latency.
     -- Chris Caudle
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