Way back on December 17, 2001, Craig Cowden asked, in a question
concerning insomnia:

"Also, my students broadly know that certain foods, such as warm
milk and turkey, contain a chemical (tyramine?) that is a
precursor chemical to serotonin".

In my reply on the same day, I suggested that the chemical in
question was not tyramine but l-tryptophan, a precursor to
serotonin with alleged sleep-inducing properties. I subsequently
discovered that no less an authority than James Kalat, in the
seventh edition of his _Biological Psychology_ (2001, p. 354)
asserted, without reference, that "milk and turkey have
relatively high amounts" of tryptophan.

I thought no more than usual about this until the other day, when
I was lecturing on serotonin and sleep, and a student again
brought up turkey (the concept, not the upchuck) and
l-tryptophan.  In checking, I see that the _National
Eosinophilia-Myalgia Syndrome Network_ (at
http://www.nemsn.org/what%20caused%20EMS.htm) state "In its
natural form LT ([l-tryptophan] is an amino acid found in foods
as milk and turkey". Canada's own CBC Radio (at
http://www.cbc.ca/news/radionews/context/biotech.html) says
almost exactly the same thing.  Do you see a trend here? What is
it with turkey and l-tryptophan?

Curiously, if you go back to reports in the 1970's (e.g. Kelly,
1972; "Talking turkey", 1971], turkey was under consideration as
a treatment for psoriasis, only it was considered beneficial
because it was claimed to be a _low_ tryptophan diet.

Subsequently, it seems that someone noticed that people tend to
get sleepy after stuffing themselves at Thanksgiving. Since the
main event on that occasion is turkey, the "turkey coma" became
conventional wisdom.  Presumably someone then remembered those
over-enthusiastic claims for l-tryptophan as a sleep-inducer, and
decided to pin the blame for "turkey coma" on it. The explanation
was that turkey is high in l-tryptophan, so when we get high on
turkey, we fall asleep.  As far as I can tell, this was the
likely reason people switched from claiming that turkey was a
low-tryptophan diet to claiming it was a high-tryptophan diet.
A handy discussion of some of this, with debunking, is available
on the web (Collard, 1999).

So what's the straight dope on turkey? According to Collard
(1999), who cites sources, turkey is unexceptional in the
tryptophan department, having amounts comparable to that found in
chicken or hamburger. Yet, as she points out, we don't talk about
having a "chicken coma" or a "beef coma". A source I examined
directly (Fisher & Scogall, 1982) provides confirmation. Turkey
has about the same amount of tryptophan as in chicken, and if I'm
interpreting the table correctly, the amount is actually quite
low in comparison with other amino acids.

So the next time a student asks about turkey and l-tryptophan,
tell 'em it just ain't so.

-Stephen

References

Talking Turkey (1971). The Lancet, December 25, 1410-1411

Kelly, A. (1972). Turkey diet regime in the treatment of
  psoriasis.  British Journal of Dermatology, 86, 440-441

Collard, C. (1999). Turkey gets a bad rap: is it really a "turkey
  coma"? Website of the University of Florida College of
  Pharmacy, Virtual Drug Information Center http://www.cop.ufl.edu/vdis/

Fisher, C., & Scougall, R. (1982). A note on the amino acid
  composition of the turkey. British Poultry Science, 23, 233-37.

------------------------------------------------------------------------
Stephen Black, Ph.D.                      tel: (819) 822-9600 ext 2470
Department of Psychology                  fax: (819) 822-9661
Bishop's University                    e-mail: [EMAIL PROTECTED]
Lennoxville, QC
J1M 1Z7
Canada     Department web page at http://www.ubishops.ca/ccc/div/soc/psy
           Check out TIPS listserv for teachers of psychology at:
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