Hi Dennis,
 
Thanks for all of your work. This study looks (on the surface) a lot sounder. I'll try to get a copy so that I can peruse it in more detail. It still seems that the greatest effect size was from the placebo effect but it would be interesting to see if there is really something else going on as well.
 
I really like your idea for a grant proposal. If you need a co-investigator be sure to give me a call.
 
-Don.
----- Original Message -----
Sent: Thursday, October 03, 2002 11:58 AM
Subject: RE: Student question

Don,
 
Sorry, I pulled the wrong abstract for my last post. As I scanned the titles I looked for a North American journal thinking that it would be easier for most on this list (not all, I know) to find in their libraries. (I will need interlibrary loan for any of them.) Here is an abstract for a double-blind study that was published in Scandinavia. The abstract reports a substantial placebo effect with an additional effect for the wrist placement. As you can guess, I have not read the study so I cannot attest to the quality of the research design.
 
I was very skeptical about the effectiveness of these wristbands until I started hearing about their use to reduce morning sickness. That caused me to look a little more closely at the early research. That quick look and some of the abstracts in my current look at PubMed suggests that there is something going on. It might be largely a placebo effect, but there seems to be a little added effect.
 
Any funding agencies looking in: We could design a a well controlled randomized double-blind trial for sea sickness. All we need is exclusive use of a cruise ship for a month or so....
 
My best
 
Dennis
 
Scand J Prim Health Care 2001 Mar;19(1):43-7

Acupressure treatment of morning sickness in pregnancy. A randomized, double-blind, placebo-controlled study.

Norheim AJ, Pedersen EJ, Fonnebo V, Berge L.

Havnegata General Practice, Harstad, Norway.

OBJECTIVE: To find out whether acupressure wristband can alleviate nausea and vomiting in early pregnancy. DESIGN: Double-blind, placebo-controlled study. SUBJECTS: 97 women with mean gestational length completed 8-12 weeks. MAIN OUTCOME MEASURES: Symptoms were recorded according to intensity, duration and nature of complaints. RESULTS: 71% of women in the intervention group reported both less intensive morning sickness and reduced duration of symptoms. The same tendency was seen in the placebo group, with 59% reporting less intensity and 63% shorter duration of symptoms. However, a significance level of 5% was reached only in the case of duration of symptoms, which was reduced by 2.74 hours in the intervention group compared to 0.85 hours in the placebo group (p = 0.018). CONCLUSIONS: Acupressure wristband might be an alternative therapy for morning sickness in early pregnancy, especially before pharmaceutical treatment is considered.
 
-----Original Message-----
From: don allen [mailto:[EMAIL PROTECTED]]
Sent: Thursday, October 03, 2002 2:20 PM
To: Teaching in the Psychological Sciences
Subject: Re: Student question

Dennis-
 
It will be a while before I can get a copy of the article you mention, but my first concern would be that it appears NOT to be a double-blind study. Placebo control is important, but if the person administering the placebo has knowledge of the treatment/placebo status this may compromise the study. EEE effects are always a danger. I'd take this study with a very large grain of salt. Were there other studies which included all of the proper controls?
 
-Don.
 
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