Hey folks:

I have a student who is interested in doing some research investigating
the impact of home schooling on social and emotional development.  I
don't know a whole lot about this area, so we are both in the
exploratory stages.  I'll be doing a literature search later this week,
but I'm curious if anyone on the list has done research in this area or
knows of any additional resources.  We have a lot of home-schooled
students at our university, so we have a pretty good sample of
convenience.  I've always suspected, just based on anecdotal evidence,
that there are some meaningful differences between our home-schooled and
non-home-schooled students, but it looks like we'll now have a chance to
do something a bit more scientific...

Thanks in advance!

Rod

______________________________________________
Roderick D. Hetzel, Ph.D.
Department of Psychology
LeTourneau University
Post Office Box 7001
2100 South Mobberly Avenue
Longview, Texas  75607-7001
 
Office:   Education Center 218
Phone:    903-233-3893
Fax:      903-233-3851
Email:    [EMAIL PROTECTED]


> -----Original Message-----
> From: David Epstein [mailto:[EMAIL PROTECTED] 
> Sent: Wednesday, September 03, 2003 1:42 PM
> To: Teaching in the Psychological Sciences
> Subject: Re: Serotonin production in the colon
> 
> 
> On Wed, 3 Sep 2003, Nathalie Cote went:
> 
> > One of my Intro Psych students told me that he found a Web 
> site that 
> > says that the gastrointestinal tract is a bigger producer 
> of serotonin 
> > than the brain is
> 
> That's what I've been taught--that 90% of the body's 
> serotonin is in the gut, where it serves functions related to 
> intestinal motility.
> 
> > The student is concerned because he has had his colon removed for 
> > medical reasons, so he wants to know if that affects 
> serotonin levels 
> > in his brain.
> 
> No, there's nothing to worry about there.  Serotonin doesn't 
> penetrate the blood-brain barrier, so the student's digestive 
> tract can make as much (or as little) serotonin as it likes, 
> and his brain won't know the difference, so to speak.
> 
> Serotonin in the brain is made in specific clusters of neuron 
> in the brainstem, whose axons form specific pathways with 
> specific (perhaps even opposing) functions in various other 
> brain regions.  It's not something that the brain needs to be 
> globally bathed in, like cerebrospinal fluid, and more isn't 
> necessarily better.
> 
> > 1) What do you know about serotonin in the gut? Other than 
> being the 
> > same chemical, is it related to serotonin in the brain? How?
> 
> I think that when nature finds a useful signaling molecule, 
> it uses that molecule wherever it can.  So the same molecules 
> tend to turn up in a lot of different places; that doesn't 
> have to mean they're serving the same functions.
> 
> > 2) The Web site above also makes the claim that "inadequate 
> levels of 
> > serotonin and norepinephrine precursors in the diet
> 
> ...probably constitute a condition that almost never occurs.
> 
> > is it the case that extended use of SSRIs depletes 
> neurotransmitters?
> 
> No--at least, it's never been demonstrated.  There are 
> studies showing that huge overdoses of SSRIs can damage 
> serotonergic axons in rats. Those studies have no 
> implications for chronic use of therapeutic doses.
> 
> > And is it the case that diet has a measurable effect on 
> > neurotransmitter levels in the brain?
> 
> Generally not, unless you go to unusual lengths, such as 
> fasting, then drinking specially made cocktails of amino 
> acids from which tryptophan is deliberately excluded.
> 
> --David Epstein
>   [EMAIL PROTECTED]
> 
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