Thank you, Stephen and Scott -

Your responses have helped me to hone my own thoughts on this issue. 

I am happy to have learned about "The Scientific Review of Mental Health 
Practice" serendipitously via Scott's signature. I have a paper inside me that 
is just waiting to find concrete expression. Looks as though I may have found 
an appropriate publication venue.    

Now, sigh, I must get back to this final stack of papers. 

Sandra


In a message dated 12/6/2004 11:03:50 AM Eastern Standard Time, Scott 
Lilienfeld <[EMAIL PROTECTED]> writes:

>My reading of the human literature is that the research evidence for 
>gene-environment interaction (in the sense of a statistical interaction, 
>not gene-environment "transaction," which I suspect most of us now 
>accept as a truism) is still fairly sparse. �In the domain of antisocial 
>behavior/criminality, such interactions have been detected in some, but 
>not all, studies, and Caspi, Moffitt, and colleagues have of course 
>reported widely publicized data for gene-environment interactions for 
>depression (although these important findings await replication). �In 
>other psychopathological domains (e.g., schizophrenia, alcoholism), 
>there is strong evidence for genetic and environmental main effects, but 
>still relatively little for gene-environment interactions (although such 
>interactions are difficult to detect because of statistical power 
>considerations)....Scott
>
>Stephen Black wrote:
>
>>I'll try to reply to to both Sandra's and Allen's queries together 
>>here:
>>
>>First Sandra said:
>>
>>"What about the "diasthesis-stress model", in which a psychological 
>>or physiological vulnerability interacts with environmental stressors 
>>to precipitate symptoms; both psychological (and most likely 
>>physiological, although I don't think this model specifies this 
>>dimensional outcome)? It seems to me that the preponderance of 
>>evidence supports a high degree of interaction of nature-nurture."
>>
>>My description of the true medical model as a procedure which uses 
>>symptoms to identify (diagnose) a real underlying structural cause of 
>>a disorder doesn't have a problem with this. Presumably the 
>>environmental stressors lead to structural changes in the nervous 
>>system which can at least potentially be identified (e.g. a decrease 
>>in certain neurotransmitters). �But if what is proposed is that the 
>>stressors lead to symptoms interpreted as causing a change in ego 
>>strength, then this would be an application of the quasi-medical 
>>model, which seeks not a real cause, but a hypothetical, metaphoric, 
>>and imaginary one. 
>>
>> In addition, the application of the medical model happily co-exists 
>>with the behavioural model, which says that, �even in the presence of 
>>a particular defect in the nervous system, the form which the 
>>particular symptoms take and what can be done about them is 
>>responsive to contingencies of reinforcement and other learning 
>>variables. For example, Down syndrome is caused by a genetic defect, 
>>but outcome can be improved by effective training.
>>
>>In a follow-up post, Sandra then asked:
>>
>> �
>>
>>>So. . . . �is this a medical model?> 
>>>
>>>Psychopharmacology (Berl). 2004 Aug;174(4):463-76. Epub 2004 Apr 16. � 
>>>Human genetics of plasma dopamine beta-hydroxylase activity: applications to 
>>>research in psychiatry and neurology.
>>> � �
>>>
>>>Some biochemical and 
>>>genetic studies suggest associations between low plasma or CSF DbetaH and 
>>>psychotic symptoms in several psychiatric disorders. 
>>> � �
>>>
>>
>>Definitely. 
>>
>>Then Allen hit me with:
>> �
>>
>>>(a) In a mental disorder such as schizophrenia there may be (almost
>>>certainly are) a number of factors, e.g., genetic propensity, occurrences
>>>in the womb before birth, adverse life experiences, regular ingesting of
>>>"recreational" drugs in susceptible individuals, and so on.
>>> � �
>>>
>>
>>If the working hypothesis is that these factors (genetic propensity, 
>>prenatal insult, adverse life experiences, drug adventures) alter the 
>>nervous system in ways that are at least potentially identifiable, 
>>then we're dealing with a use of the true medical model. If they 
>>cause the id to seize control of the personality, not.
>>
>>The point of this terminology isn't really directed at what standard 
>>medical investigation does, because that's pretty clear. But 
>>psychodynamic theorists have a whole vocabulary (e.g. 
>>psychopathology, mental illness, diseased mind, treating patients) 
>>and a procedure (observe symptoms and then reach a diagnosis of the 
>>underlying cause) which suggests that they're doing the same thing. 
>>This leads to confusion. People recognize that medicine has had 
>>enormous success in treatment, and if psychotherapists are doing the 
>>same thing, then their treatments must be equally respected. But 
>>they're not doing the same thing. Doctors search for real causes; 
>>psychotherapists search for metaphoric ones. So it's better to 
>>describe the procedures of psychotherapists as "quasi-medical"; that 
>>is, as imitating and having the superficial appearance of doing what 
>>doctors do, without the substance.
>>
>>Stephen
>>
>>___________________________________________________
>>Stephen L. Black, Ph.D. � � � � � �tel: �(819) 822-9600 ext 2470
>>Department of Psychology � � � � fax: �(819) 822-9661
>>Bishop's �University � � � � � � �e-mail: [EMAIL PROTECTED]
>>Lennoxville, QC �J1M 1Z7
>>Canada
>>
>>Dept web page at http://www.ubishops.ca/ccc/div/soc/psy
>>TIPS discussion list for psychology teachers at
>> http://faculty.frostburg.edu/psyc/southerly/tips/index.htm � �
>>_______________________________________________
>>
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>
>-- 
>Scott O. Lilienfeld, Ph.D.
>Associate Professor 
>Department of Psychology, Room 206 
>Emory University
>532 N. Kilgo Circle 
>Atlanta, Georgia 30322
>
>(404) 727-1125 (phone)
>(404) 727-0372 (FAX)
>
>Home Page: http://www.emory.edu/PSYCH/Faculty/lilienfeld.html
>
>The Scientific Review of Mental Health Practice:
>
>www.srmhp.org
>
>
>The Master in the Art of Living makes little distinction between his work and 
>his play, his labor and his leisure, his mind and his body, his education and 
>his recreation, his love and his intellectual passions. �He hardly knows which 
>is which. �He simply pursues his vision of excellence in whatever he does, 
>leaving others to decide whether he is working or playing. �To him - he is 
>always doing both.
>
>- Zen Buddhist text 
> �(slightly modified) 
>
>
>
>
>
>
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