Paul Okami asked, "Can anyone point me in the direction of data, graphs or 
charts of trends in the extent of antidepressant use in the US over the past 
two decades?"


>From the National Center for Health Statistics.

"Health, United States, 2007 with Chartbook on Trends in the Health of 
Americans" (http://www.cdc.gov/nchs/data/hus/hus07.pdf ) says this on page 106 
in pdf pages (page 88 in document pages):

Antidepressant Drugs: Adults
Non-Hispanic white women are more likely to have used antidepressant drugs in 
the past month than non-
Hispanic black women or women of Mexican origin.
Depression and other forms of mental illness are critical public health issues 
in America today. In 2001-2002, an
estimated 16% of noninstitutionalized adults had a major depressive disorder at 
some point in their lifetime, with 7%
having had a major depressive episode during the 12 months prior to interview 
(1). The detrimental effects of depressive
symptoms on quality of life and daily functioning have been estimated to equal 
or exceed those of heart disease and
exceed those of diabetes, arthritis, and gastrointestinal disorders (2,3). 
Access to both accurate diagnosis and
appropriate treatment of depression is necessary to combat this prevalent and 
debilitating disease.

Prescriptions for antidepressants have been rising, associated with the 
introduction in 1988 of a new class of drugs known
as selective serotonin reuptake inhibitors (SSRIs) (4). Current SSRIs include 
the brand names CelexaT, LexaproT, LuvoxT,
PaxilT, ProzacT, and ZoloftT. In addition to their use as antidepressants, 
SSRIs are approved and marketed for the
treatment of other mental disorders including obsessive compulsive disorder, 
panic disorder, anxiety disorders, and
premenstrual dysphoric disorder. The substantial increase in prescriptions for 
antidepressants also suggests widespread
''off-label'' (other than FDA-approved uses) use for subsyndromal mental health 
conditions and a variety of
physical disorders (5,6).

Between 1988-1994 and 1999-2002 the percentage of adults in the civilian 
noninstitutionalized population who reported
using an antidepressant drug during the past month more than tripled, 
increasing from 2.5% to 8.0% (age-adjusted;
data table for Figure 36, Technical Notes). Use among women rose from 3.3% to 
10.6% and use among men from 1.6% to
5.2%. In both time periods, antidepressant use by women was about twice that of 
men.

In 1999-2002, the percentage of non-Hispanic white adults who reported the use 
of antidepressants was more than
double that reported by non-Hispanic black and Mexican adults. Nearly 13% of 
non-Hispanic white women reported
use of antidepressants in the past month, compared with about 5% of 
non-Hispanic black and Mexican women. In the
same time period, 6% of non-Hispanic white men reported antidepressant drug use 
in the past month, compared with
about 3% of non-Hispanic black men and less than 2% of men of Mexican origin. 
Disparities in the diagnosis of
depression of black and Hispanic patients compared to white patients may have 
narrowed in recent years. However, racial
or ethnic disparities in the treatment-including prescriptions for 
antidepressant drugs-of depression once diagnosed
persist (7). Black and Hispanic patients who have been diagnosed with 
depression are less likely to obtain counseling
and drug therapy to treat their depression than are white patients. Factors 
contributing to this disparity may include a
belief by more African American and Hispanic persons than white persons that 
antidepressant therapy is unacceptable or
ineffective, a preference for other types of therapy, or financial and 
insurance barriers to obtaining treatment (7,8).
References
1. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, et al. The 
epidemiology of major depressive
disorder: Results from the National Comorbidity Survey Replication (NCS-R). 
JAMA 2003;289(23):3095-105.
2. Wells KB, Stewart A, Hays RD, Burnam MA, Rogers W, Daniels M, et al. The 
functioning and well-being of depressed
patients: Results from the Medical Outcomes Study. JAMA 1989;262(7):914-9.
3. Burvill PW. Recent progress in the epidemiology of major depression. 
Epidemiol Rev 1995;17(1):21-31.
4. Pincus HA, Tanielian TL, Marcus SC, Olfson M, Zarin DA, Thompson J, et al. 
Prescribing trends in psychotropic
medications: Primary care, psychiatry, and other medical specialties. JAMA 
1998;279(7):526-31.
5. Foote SM, Etheredge L. Increasing use of new prescription drugs: A case 
study. Health Aff 2000;19(4):165-70.
6. Stone KJ, Viera AJ, Parman CL. Off-label applications for SSRIs. Am Fam 
Physician 2003;68(3):498-504.
7. Miranda J, Cooper LA. Disparities in care for depression among primary care 
patients. J Gen Intern Med
2004;19(2):120-6.
8. Schraufnagel TJ, Wagner AW, Miranda J, Roy-Byrne PP. Treating minority 
patients with depression and anxiety: What
does the evidence tell us? Gen Hosp Psychiatry 2006 Jan-Feb;28(1):27-36. 

--
Sue Frantz                 Highline Community College       
Psychology                Des Moines, WA
206.878.3710 x3404    [EMAIL PROTECTED]
http://flightline.highline.edu/sfrantz/ 
--
APA Division 2: Society for the Teaching of Psychology
http://teachpsych.org/
Office of Teaching Resources in Psychology
Associate Director
Project Syllabus
http://teachpsych.org/otrp/syllabi/syllabi.php

 

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