Shoenen, J. et al Neurology 1998; 50: 466-470 reports that riboflavin (400 mg daily) was significantly effective as a migraine prophylaxis. The suspected reason was that riboflavin improved mitochondrial energy metabolism. Oliver Sacks suggested in his book on Migraines that migraines and epilepsy were connected. This raises the question would riboflavin help control epilepsy? Correlational Opponent Processing model suggest that pain is due to discrepant information on two or more multiple channels of sensory/motor information. This raises the question would riboflavin help improved learning and memory? Ron Blue
