I didn't mean to sound critical of the messenger.  Sorry if it 
came off that way.

I think placebo effects are quite real and that the use of 
placebo trials is essential to understanding the efficacy of 
pharmaceutical and psychological treatments.  Placebo trials 
force us to examine the whole person/system, rather than just 
the disease.  Personality, attitude, belief systems, stress 
and coping skills, all have a very real impact on the state of 
the physical body (I can't believe I said that--I deplore 
dualism--body is mind and mind is body. Hmmm, how can I explain
this...?).  What I mean to say is that I do not discount the
possibility of psychological contributions to disease.  What
I do object to is anecdotal evidence that can too easily be 
misinterpreted by an audience unpracticed in scientific inquiry.

Placebo effects in pain is a very interesting area.  In 
Dennis's example below, the author didn't claim to cure 
arthritis or to reduce inflammation and joint damage.  The 
claim was that the sham surgery alleviated pain.  Pain 
management can often be accomplished without changing the 
state of the injured or diseased area, so this type of 
placebo effect seems somewhat different than those that
appear to eliminate evidence of disease.  

I can't help wondering if patients in double blind clinical 
trials spend their darkest moments wondering if they got the 
real stuff.  Is there a better way to do this?

All my best,

Pam


Dennis Goff wrote:

> I agree with Pam's warning; however, there are clinical trials of "placebo
> surgery" for the treatment of disorders other than Cancer and Parkinson's.
> There was a story in the New York Times Magazine that described the success
> of sham surgery for the treatment of arthritic pain in the knees (reference
> information below). I tried a medline search to find a reference to a
> refereed citation but did not have any luck.
>
> Dennis

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