How has this flown under the TIPS radar (or did I miss the discussion).

I've generally found Begley a solid skeptical scientific writer, providing high 
quality summaries of scientific work. But, found this article not so 
satisfying. Worse was the counterpoint by a doctor who used the argument none 
(I hope) of us would support: 'Antidepressants worked for my patients and it 
worked for me!'

The most annoying point was when Begley said that the serotonin link to 
depression is not established (called it "built on a foundation of tissue 
paper"). She said it was based in an old association from an early 
anti-depressant drug and that there has not been any good scientific support 
for there being reduced serotonin levels or activity in persons who are 
depressed. 

I'm hoping someone here knows better. Because it is not a core area for me I 
have no citable sources.

Link to the article: http://www.newsweek.com/id/232781

Paul C. Bernhardt
Department of Psychology
Frostburg State University
Frostburg, Maryland

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