The appearances of the amyloid plaques & dendritic tangles would constitute a 
pre-clinical stage. Neural pathologies are present but obvious behavioral 
symptoms have not occurred.



I see it as no different than saying that I have coronary artery disease even 
though I have not yet developed angina pectoris or a myocardial infarction.   
And no different than being diagnosed with type II diabetes because my blood 
glucose is high even though I have not developed any other symptoms.



Edward I. Pollak, Ph.D.
Department of Psychology
West Chester University of Pennsylvania
Office hours: Mondays noon-2 & 3-4; Tuesdays & Thursdays 8-9:15 & 12:30-2
http://home.comcast.net/~epollak/home.htm
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Husband, father, grandfather, biopsychologist, & bluegrass fiddler...... in 
approximate order of importance.

Subject: Puzzling Alzheimers diagnosis
From: "michael sylvester" <[email protected]>
Date: Sun, 24 Apr 2011 16:12:32 -0100
X-Message-Number: 1

The new guidelines for evaluating Alzm distinguish among three stages,namely,a 
pre-clinical.mild cognitive impairment,and dementia.It is the 
pre-clinical(stage without symptoms) that I find puzzling.It would seem that if 
there are no symptoms  that condition does not deserve to be called a stage.Or 
virtually all conditions will have a pre-clinical stage.I guess we are all in a 
pre-clinical stage for developping schizophrenia. Come on,I can envision a 
post-clinical stage,but pre-clinical?


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