The NY Times has an interesting article on some ecological research focusing
on how Lyme disease might be disseminated through an ecosystem.  The
relationships are complex and correlational (which is acknowledged) but, given
the severity of the nature of the problem, may lead to certain types of public
policies (e.g., reducing the deer population).  For the article, see:
http://green.blogs.nytimes.com/2012/06/18/predators-prey-and-lyme-disease/

The original research appear in PNAS and can be accessed here:
http://www.pnas.org/content/early/2012/06/12/1204536109

Interesting point:  the spirochete that causes Lyme disease (Borrelia
burgdorferi;
other spirochete cause other diseases like syphillis) is not present in the
deer tick, the primary transmitter of the spirochete, at birth.  Rather, when
it reaches the nymph stage and has blood meals, this is when it becomes
infected and subsequent blood meals transmit the disease. Feeding on
infected white-footed mouse seems to be the main source of infection
for the ticks.

The pattern of factors that affect the spread of Lyme is complex and, as
one researcher quoted in the article says, certain links need experimental
verification.  Another point that is made is the question why there still isn't
a vaccine for Lyme disease.  It seems to me that a human vaccine would be
best but a vaccine for animals, such as the white footed mouse, might do
much to reduce the incidence of the disease.

-Mike Palij
New York University
[email protected]

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