Remember Craig Bennett's fMRI scanning of a dead salmon and
the detection of "brain activity"?  If not, here's a refresher:
http://www.wired.com/2009/09/fmrisalmon/

There is a new study out that looks at brain activity in mice during
locomotion and it finds that not all neural areas that are active
increase their blood flow (which is a key measure in fMRI).
The reference for the article is:
Huo BX, Smith JB, Drew PJ, (2014). Neurovascular coupling
and decoupling in the cortex during voluntary locomotion.
Journal of Neuroscience, 34(33), 10975-10981.

The abstract and the full article (if you have a sub; use your
school's) are available here:
http://www.jneurosci.org/content/34/33/10975.abstract

I was alerted to this article by a mass media article about it
on the "Science News" website, however, this article is
behind a paywall ($50 for a sub to access it) and is not
yet available through NYU's library (maybe if I were on
campus but I digress).  You may have better luck than I:
https://www.sciencenews.org/article/busy-neurons-don%E2%80%99t-always-draw-blood

Here's the funny part:  I came across the Science News
article this morning and then went to the website for the
Journal of Neuroscience but they did not make available
the August 13's issue until this afternoon (the link in the
Science News article did not work this morning but I
assume it works now, that is, the doi url is now enabled).

Anyway, the lesson appears to be that one should be using
cautious in using blood flow as an indicator of cognitive
activity in the brain because neural activity does not apparently
always need increased blood flow (at least under these
conditions; you are free to speculate on how general this
result may be).

Also, sometimes one may have to wait to get access to primary
sources  because they may be embargoed for the general public
but available to others (e.g., news reporters); one will not have
the primary source available to verify the mass media account.
I think this means one should learn to cultivate patience.

-Mike Palij
New York University
[email protected]





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