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> From: CDER MEDWATCH LISTSERV <[EMAIL PROTECTED]>
> To: <[EMAIL PROTECTED]>
> Date: 7/17/2007 3:30:34 PM
> Subject: FDA MedWatch: April 2007 Monthly Safety Labeling Changes Posted
on Website
>
> MedWatch - The FDA Safety Information and Adverse Event Reporting Program
>
> The April 2007 posting includes 54 drug products with safety labeling
changes to the WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, and PATIENT
> PACKAGE INSERT/MEDICATION GUIDE sections.
>
> The Summary page -- 
>
> http://www.fda.gov/medwatch/SAFETY/2007/apr07_quickview.htm 
>
> -- provides drug names and a listing of the sections changed. 
>
> The Detailed view --
>
> http://www.fda.gov/medwatch/SAFETY/2007/apr07.htm 
>
> -- includes sections/subsections changed and a description of new or
modified safety information in the Boxed Warning, Contraindications, or
> Warnings sections. The full labeling may be accessed by clicking on the
prescribing information link below the drug's name.
>
> The following drugs had modifications to the CONTRAINDICATIONS, and/or
WARNINGS sections:
>
> Enjuvia (synthetic conjugated estrogens, B) Tablets
> Fentora (fentanyl buccal tablet)
> Ativan (lorazepam) Tablets
> Femara (letrozole tablets)
> Invirase (saquinavir mesylate) Capsules and Tablets 
> Advicor (niacin extended-release/lovastatin tablets) 
> Baraclude (entecavir) Tablets and Oral Solution
> Exjade (deferasirox) Tablets for Oral Suspension
> Levitra (vardenafil HCl) Tablets
> Minocin (minocycline hydrochloride) Pellet-Filled Capsules
> Sarafem (fluoxetine hydrochloride tablets) 
> Zerit (stavudine) Capsules and Zerit (stavudine) for Oral Solution 
> Zyvox (linezolid) Injection and Tablets and Zyvox (Iinezolid) for Oral
Suspension
>
> The following drugs had modification to patient information labeling
[either Medication Guide or Patient Package Insert]:
>
> Enjuvia (synthetic conjugated estrogens, B) Tablets
> Fentora (fentanyl buccal tablet)
> Invirase (saquinavir mesylate) Capsules and Tablets 
> Baraclude (entecavir) Tablets and Oral Solution
> Levitra (vardenafil HCl) Tablets
> Zerit (stavudine) Capsules and Zerit (stavudine) for Oral Solution 
> Actonel (risedronate sodium tablets)
> Apidra (insulin glulisine [rDNA origin] injection)
> Aranesp (darbepoetin alfa) for Injection 
> Focalin (dexmethylphenidate hydrochloride) Tablets 
> Focalin XR (dexmethylphenidate hydrochloride) Extended- Release Capsules
> Fortamet (metformin hydrochloride) Extended-Release Tablets
> Lantus (insulin glargine [rDNA origin] injection) 
> Ritalin hydrochloride (methylphenidate hydrochloride tablets, USP)
> Ritalin-SR (methylphenidate hydrochloride, USP sustained-release tablets)
> Ritalin LA (methylphenidate hydrochloride) Extended-Release Capsules 
> Singulair (montelukast sodium) Tablets, Chewable Tablets, and Oral
Granules
> Strattera (atomoxetine HCl) Capsules
> Fosamax Plus D (alendronate sodium/cholecalciferol) Tablets
> Solagé (mequinol 2%, tretinoin 0.01%) Topical Solution
> EC-Naprosyn (naproxen delayed-release tablets), Naprosyn (naproxen
tablets), Anaprox/Anaprox DS (naproxen sodium tablets), and 
> Naprosyn (naproxen suspension)
> NicoDerm CQ (nicotine transdermal system) 
>
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5:42 PM


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