I find it humorous that you make the assumption that DRM is to your
advantage. It probably isn't to your advantage as a writer to release your
epublication with DRM. You will only be limiting your customer base. If it
really is that popular it will get pirated either way. Chances are if it
isn't that popular you won't be able to afford to implement DRM around it
anyway. Without DRM it is fairly trivial to publish. With DRM someone else is
going to get a cut and you are going to limit your potential.
Generally speaking you are better of hitting the masses with a product than
trying to fill a niche in the market. :) while ThinkPenguin might be hitting
a niche today you don't think it's going to be a niche for ever do you?
Focus on the masses and stop worrying about piracy. All those non-paying
customers will only increase the publicity and in turn produce more readers.
The number of readers willing to pay might be small. However if you had 1000
reading paying for your work in a DRM format you might have 10,000 readers
without. Of that 10,000 1,500 might donate that or more of what you would
have charged on a DRM'd publication.