There are some "free software" graphics editors and similar applications
which are dependent on non-free Microsoft Windows components. These
components are non-free programs written by Microsoft, bundled in MS Windows,
and relied upon by these "free" programs. Many of these developers will not
port these applications to GNU/Linux because it isn't easy to do.
If these projects were written in a more cross-platform oriented manor this
would not be difficult. WINE is handy to port these "free" programs to
GNU/Linux because WINE is a re-implementation of these non-free Microsoft
dependencies.
There is nothing wrong with WINE. The problem is its used mostly to run
programs that aren't even mostly or partially free.