I installed Trisquel 8 from the previous alpha ISO from a few months ago. I
had trouble with the text installer, and I haven't gotten around to trying
the new ISO to see if this is fixed, but the graphical installer worked fine.
The next issue was that firmware-ath9k-htc (firmware for the ThinkPenguin
WiFi dongle) was missing, but I understand that this is fixed in the new ISO
from 12/24.
The only technical problems I encountered were when trying to install other
desktop environments. That won't be an issue if you stick to the default
desktop environment.
I've also run into some branding stuff left over from upstream, including
some Ubuntu, Debian, and Amazon icons and logos. Those don't affect usability
though. If you run into any, report them as an issue.
Trisquel 8 seems much closer to completion than is implied by it being in
alpha.